Protein: SFXN2
Sideroflexin-2

Gene: SFXN2
Organism: Homo sapiens
Interactions: 82
UniProt ID: Q96NB2

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005743 - mitochondrial inner membrane
GO:0015075 - monoatomic ion transmembrane transporter activity
GO:0022857 - transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1057646

CDK18
Cyclin-dependent kinase 18

3

2

High-throughput

0.650

High

1398923

SFXN1
Sideroflexin-1

2

4

High-throughput

0.584

High

1109021

AQP6
Aquaporin-6

2

3

High-throughput

0.553

High

1279353

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

3

High-throughput

0.553

High

1398920

REEP4
Receptor expression-enhancing protein 4

2

2

High-throughput

0.553

High

1398924

TM14B
Transmembrane protein 14B

2

2

High-throughput

0.553

High

260934

RAMP3
Receptor activity-modifying protein 3

2

2

High-throughput

0.549

High

1382369

SPSB4
SPRY domain-containing SOCS box protein 4

2

4

High-throughput

0.549

High

774568

BASI
Basigin

1

6

High-throughput

0.536

High

1098741

NDK3
Nucleoside diphosphate kinase 3

1

1

High-throughput

0.536

High

1310321

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1350864

HUMMR
Protein MGARP

1

1

High-throughput

0.536

High

62153

KLRG2
Killer cell lectin-like receptor subfamily G member 2

1

5

High-throughput

0.489

High

154865

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

2

High-throughput

0.489

High

166017

FFAR1
Free fatty acid receptor 1

1

7

High-throughput

0.489

High

182736

GP182
G-protein coupled receptor 182

1

11

High-throughput

0.489

High

211394

RFOX2
RNA binding protein fox-1 homolog 2

1

1

High-throughput

0.489

High

268935

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

1

1

High-throughput

0.489

High

317254

AL1A2
Retinal dehydrogenase 2

1

1

High-throughput

0.489

High

380339

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

4

High-throughput

0.489

High

469534

SYPH
Synaptophysin

1

2

High-throughput

0.489

High

472201

TRFM
Melanotransferrin

1

2

High-throughput

0.489

High

488340

PPBI
Intestinal-type alkaline phosphatase

1

2

High-throughput

0.489

High

538663

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

2

High-throughput

0.489

High

575693

GPIX
Platelet glycoprotein IX

1

5

High-throughput

0.489

High

627558

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

4

High-throughput

0.489

High

733053

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

1

High-throughput

0.489

High

749378

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

2

High-throughput

0.489

High

845108

EAA3
Excitatory amino acid transporter 3

1

3

High-throughput

0.489

High

873371

AL3B2
Aldehyde dehydrogenase family 3 member B2

1

3

High-throughput

0.489

High

1034802

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

2

High-throughput

0.489

High

1036240

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

1

High-throughput

0.489

High

1086085

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

1

High-throughput

0.489

High

1310195

SFPA2
Pulmonary surfactant-associated protein A2

1

1

High-throughput

0.489

High

1324847

LRC25
Leucine-rich repeat-containing protein 25

1

1

High-throughput

0.489

High

1336521

LRN4L
LRRN4 C-terminal-like protein

1

1

High-throughput

0.489

High

1337125

HIPK4
Homeodomain-interacting protein kinase 4

1

1

High-throughput

0.489

High

1398916

THTPA
Thiamine-triphosphatase

1

1

High-throughput

0.489

High

1398926

TSP50
Probable threonine protease PRSS50

1

7

High-throughput

0.489

High

1398927

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.489

High

1398929

NPTN
Neuroplastin

1

6

High-throughput

0.489

High

1199821

AGK
Acylglycerol kinase, mitochondrial

1

1

Small-scale

0.479

High

831262

CCNF
Cyclin-F

1

3

High-throughput

0.470

High

880861

NRAM2
Natural resistance-associated macrophage protein 2

1

1

High-throughput

0.445

High

1325899

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

1

High-throughput

0.445

High

174587

TRI66
Tripartite motif-containing protein 66

1

1

High-throughput

0.437

High

294199

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

342294

BRD1
Bromodomain-containing protein 1

1

1

High-throughput

0.437

High

589447

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

659282

SP100
Nuclear autoantigen Sp-100

1

1

High-throughput

0.437

High

696251

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

714361

PML
Protein PML

1

5

High-throughput

0.437

High

724702

MK04
Mitogen-activated protein kinase 4

1

2

High-throughput

0.437

High

768927

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

970937

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

1114042

CUL3
Cullin-3

1

3

High-throughput

0.437

High

1252939

BAKOR
Beclin 1-associated autophagy-related key regulator

1

3

High-throughput

0.437

High

1397323

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.437

High

1398915

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.437

High

1398917

SPRTN
DNA-dependent metalloprotease SPRTN

1

2

High-throughput

0.437

High

1398918

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.437

High

1398919

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1398921

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.437

High

1398922

EXO5
Exonuclease V

1

1

Small-scale

0.437

High

1398925

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.437

High

653514

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

270841

ROCK2
Rho-associated protein kinase 2

1

2

High-throughput

0.407

High

944036

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.407

High

1398928

S35A3
UDP-N-acetylglucosamine transporter

1

1

High-throughput

0.407

High

1094866

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

49747

TMM72
Transmembrane protein 72

1

0

High-throughput

0.279

Low

289334

FCN3
Ficolin-3

1

0

High-throughput

0.279

Low

635366

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.279

Low

956099

SPCS3
Signal peptidase complex subunit 3

1

0

High-throughput

0.279

Low

1159226

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.279

Low

1359094

ITLN1
Intelectin-1

1

0

High-throughput

0.279

Low

255472

SNX2
Sorting nexin-2

1

0

High-throughput

0.249

Low

767306

MERL
Merlin

1

0

High-throughput

0.249

Low

908163

KS6A3
Ribosomal protein S6 kinase alpha-3

1

0

High-throughput

0.249

Low

1178316

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1306911

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.249

Low

1386472

KLH29
Kelch-like protein 29

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025