HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: CHM4B (Q9H444)
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Gene: CHMP4B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 224
+	Hs
		261308 FLNB_HUMAN (1-2602): 0: 2855: 100.00		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		598318 FLNA_HUMAN (1-2602): 0: 2661: 69.59		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		598265 FLNA_HUMAN (1-2602): 0: 2661: 69.59		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		1052937 FLNC_HUMAN (6-2602): 0: 1470: 35.38		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		1052920 FLNC_HUMAN (6-2602): 0: 1470: 35.38		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		993293 ACTN3_HUMAN (5-364): 1.21e-118: 402: 26.88		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		521612 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		725696 ACTN2_HUMAN (5-364): 2.6e-116: 395: 26.61		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		993280 ACTN3_HUMAN (5-364): 1.21e-118: 402: 26.88		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		963414 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		211663 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		521595 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		725686 ACTN2_HUMAN (5-364): 2.6e-116: 395: 26.61		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		963386 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		211642 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		506841 SPTB1_HUMAN (6-282): 2.13e-95: 347: 32.14		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		506831 SPTB1_HUMAN (6-282): 2.13e-95: 347: 32.14		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		1286754 MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78