HitPredict

Interactor 1: NCOR1 (O75376)
Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)
Gene: NCOR1

Interactor 2: CEBPB (P17676)
CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5)
Gene: CEBPB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30884312, 15870285
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000976 - transcription cis-regulatory region binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0042826 - histone deacetylase binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2440 Hs			1 345
+	Hs
		261438 NCOR1_HUMAN (1-2440): 0: 780: 100.00		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		570236 NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71		CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00
+	Hs
		831855 NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		570166 RCOR1_HUMAN (360-717): 6.64e-75: 260: 19.40		CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00
+	Hs
		831783 RCOR1_HUMAN (360-717): 6.64e-75: 260: 19.40		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		554262 MUC1_HUMAN (1783-2434): 1.7e-42: 173: 12.71		CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00
+	Hs
		569294 MYH9_HUMAN (302-1007): 2.78e-26: 121: 11.05		CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00
+	Hs
		831502 KMT2C_HUMAN (1352-2176): 4.42e-47: 190: 15.30		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		569978 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00
+	Mm
		862863 MYH9_MOUSE (302-1007): 5.2e-27: 123: 11.05		CEBPA_MOUSE (24-345): 2.92e-47: 165: 29.79
+	Hs
		831618 MINT_HUMAN (468-2394): 3.2e-23: 111: 8.72		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		831611 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49
+	Hs
		831924 MINT_HUMAN (468-2394): 3.2e-23: 111: 8.72		CEBPD_HUMAN (46-344): 1.55e-36: 134: 28.43
+	Hs
		831922 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		CEBPD_HUMAN (46-344): 1.55e-36: 134: 28.43
+	Hs
		568277 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		ATF7_HUMAN (92-342): 1.66e-28: 117: 21.64
+	Hs
		973616 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		CREB5_HUMAN (16-342): 4.28e-24: 104: 12.20
+	Dm
		1370284 Q9VLS7_DROME (1707-2440): 4.88e-11: 70.8: 8.45		Q9VTE8_DROME (251-333): 2.61e-15: 73.2: 27.06