HitPredict

Interactor 1: VAMP4 (O75379)
Vesicle-associated membrane protein 4 (VAMP-4)
Gene: VAMP4

Interactor 2: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 141 Hs			1 218
+	Hs
		261647 VAMP4_HUMAN (1-120): 4.03e-40: 132: 100.00		RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92
+	Hs
		850551 VAMP7_HUMAN (15-139): 2.43e-33: 118: 27.20		RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92
+	Hs
		261649 VAMP4_HUMAN (1-120): 4.03e-40: 132: 100.00		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Dm
		577228 SYB_DROME (24-135): 9.5e-32: 112: 26.79		Q7KY04_DROME (6-216): 7.32e-92: 269: 77.25
+	Hs
		591780 VAMP7_HUMAN (15-139): 2.43e-33: 118: 27.20		RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00
+	Hs
		895094 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92
+	Hs
		895029 VAMP2_HUMAN (46-122): 9.98e-26: 95.5: 35.07		RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92
+	Hs
		850554 VAMP7_HUMAN (15-139): 2.43e-33: 118: 27.20		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		591860 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00
+	Hs
		591808 VAMP2_HUMAN (46-122): 9.98e-26: 95.5: 35.07		RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00
+	Hs
		591996 VAMP8_HUMAN (41-120): 1.87e-25: 94.3: 27.50		RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00
+	Hs
		918878 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43
+	Hs
		896624 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RAB14_HUMAN (3-217): 2.42e-84: 250: 57.21
+	Hs
		1079324 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26
+	Hs
		914092 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		913996 VAMP2_HUMAN (46-122): 9.98e-26: 95.5: 35.07		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		926211 VAMP2_HUMAN (46-122): 9.98e-26: 95.5: 35.07		RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26
+	Hs
		914322 VAMP8_HUMAN (41-120): 1.87e-25: 94.3: 27.50		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		1079428 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RAB1B_HUMAN (6-218): 6.6e-83: 246: 39.44
+	Sc
		350845 SEC22_YEAST (23-133): 3.08e-25: 97: 17.12		YPT1_YEAST (6-184): 3.71e-54: 174: 48.05