HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: SNAG (Q99747)
Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma)
Gene: NAPG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNAP~Synaptobrevin
Common GO terms	GO:0031201 - SNARE complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 312
+	Hs
		263203 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		SNAA_HUMAN (22-275): 5.22e-67: 213: 20.93
+	Hs
		850592 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		SNAG_HUMAN (1-312): 3.66e-87: 265: 100.00
+	Dm
		115822 M9PGI6_DROME (1-215): 2.77e-76: 230: 56.22		Q9U6R9_DROME (1-312): 3.86e-71: 224: 38.14
+	Dm
		115802 M9PGI6_DROME (1-215): 2.77e-76: 230: 56.22		SNAP_DROME (6-279): 1.99e-65: 209: 17.96
+	Hs
		180923 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		SNAG_HUMAN (1-312): 3.66e-87: 265: 100.00
+	Zm
		31296 A0A1D6KH00_MAIZE (25-215): 2.1e-70: 227: 18.65		A0A1D6PZ82_MAIZE (6-262): 1.94e-62: 203: 22.22
+	Dm
		115828 M9PGI6_DROME (1-215): 2.77e-76: 230: 56.22		Q9VH25_DROME (1-290): 3.1e-59: 193: 29.66
+	Dm
		1178116 Q7JYX5_DROME (30-214): 7.52e-63: 196: 20.54		Q9U6R9_DROME (1-312): 3.86e-71: 224: 38.14
+	Hs
		850546 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		SNAA_HUMAN (22-275): 5.22e-67: 213: 20.93
+	Dm
		1095560 Q7JYX5_DROME (30-214): 7.52e-63: 196: 20.54		SNAP_DROME (6-279): 1.99e-65: 209: 17.96
+	Sc
		605825 SEC22_YEAST (1-215): 1.97e-66: 205: 35.65		SEC17_YEAST (6-276): 1.43e-56: 186: 20.14
+	Dm
		1178122 Q7JYX5_DROME (30-214): 7.52e-63: 196: 20.54		Q9VH25_DROME (1-290): 3.1e-59: 193: 29.66
+	Hs
		180842 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		SNAA_HUMAN (22-275): 5.22e-67: 213: 20.93
+	Dm
		1353755 Q9W3M8_DROME (28-188): 3.61e-45: 150: 20.25		Q9U6R9_DROME (1-312): 3.86e-71: 224: 38.14
+	Dm
		1095592 Q9W3M8_DROME (28-188): 3.61e-45: 150: 20.25		SNAP_DROME (6-279): 1.99e-65: 209: 17.96
+	Dm
		1366632 Q9W3M8_DROME (28-188): 3.61e-45: 150: 20.25		Q9VH25_DROME (1-290): 3.1e-59: 193: 29.66
+	Sc
		696563 YKT6_YEAST (31-188): 1.64e-44: 148: 24.54		SEC17_YEAST (6-276): 1.43e-56: 186: 20.14
+	Hs
		111025 I1VE18_HUMAN (63-115): 1.09e-21: 85.8: 98.11		SNAA_HUMAN (22-275): 5.22e-67: 213: 20.93