HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 648
+	Hs
		373636 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		154726 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374703 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		542811 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88
+	Hs
		373791 MYH10_HUMAN (432-957): 1.68e-14: 80.8: 9.98		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		125075 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		488559 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		373794 MYH11_HUMAN (528-957): 1.19e-11: 71.1: 10.42		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		373790 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		542908 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88
+	Hs
		488778 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		542914 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88
+	Hs
		125134 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88
+	Hs
		411983 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		FYN_HUMAN (337-607): 2.33e-103: 326: 34.55
+	Hs
		433283 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		YES_HUMAN (329-607): 1.22e-105: 332: 33.92
+	Hs
		1217973 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		KSR1_HUMAN (138-648): 6.15e-108: 348: 24.61
+	Hs
		412307 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		FYN_HUMAN (337-607): 2.33e-103: 326: 34.55
+	Hs
		111443 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		J3QRU1_HUMAN (329-607): 1.4e-105: 332: 33.92
+	Hs
		433272 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		YES_HUMAN (329-607): 1.22e-105: 332: 33.92
+	Hs
		412058 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		FYN_HUMAN (337-607): 2.33e-103: 326: 34.55