HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.719

Property	Details
Experiments	9700202, 15383276, 32814053, 17161366, 17500595
Identification Methods	pull down, two hybrid, validated two hybrid, nuclear magnetic resonance, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 3142
+	Hs
		154758 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		269209 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791868 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		125219 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791664 PR40B_HUMAN (89-509): 1.89e-12: 73.5: 23.64		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Mm
		103047 MYH10_MOUSE (432-957): 2.7e-14: 80: 9.61		G3X9H5_MOUSE (81-3142): 0: 5479: 91.19
+	Mm
		93870 E9QPE7_MOUSE (528-957): 7.11e-11: 68.8: 11.72		G3X9H5_MOUSE (81-3142): 0: 5479: 91.19