HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16055720
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016020 - membrane GO:0016363 - nuclear matrix GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 471
+	Hs
		263758 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		263519 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		154809 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		NONO_HUMAN (1-471): 1.15e-97: 303: 100.00
+	Hs
		808625 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		NONO_HUMAN (1-471): 1.15e-97: 303: 100.00
+	Mm
		93571 DESP_MOUSE (362-952): 1.3e-61: 231: 13.30		SFPQ_MOUSE (23-471): 7.21e-54: 193: 55.72
+	Hs
		269236 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		NONO_HUMAN (1-471): 1.15e-97: 303: 100.00
+	Hs
		154847 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		516402 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		1069788 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		NONO_HUMAN (1-471): 1.15e-97: 303: 100.00
+	Hs
		808925 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP3_HUMAN (66-459): 5.94e-61: 211: 13.88
+	Hs
		154746 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		613369 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		269259 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		269201 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		154816 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		516643 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		269204 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		125122 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		1077493 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Sc
		376704 PRP40_YEAST (144-667): 4.38e-18: 91.1: 16.90		PABP_YEAST (30-384): 3.77e-37: 145: 16.50