HitPredict

Interactor 1: TACC1 (O75410)
Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)
Gene: TACC1

Interactor 2: ERBB3 (P21860)
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
Gene: ERBB3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 805 Hs			1 1342
+	Hs
		601934 TENS2_HUMAN (31-532): 2.18e-36: 150: 11.71		ERBB3_HUMAN (1-1342): 0: 1388: 100.00
+	Hs
		263987 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		ERBB2_HUMAN (25-1222): 0: 1067: 39.95
+	Hs
		1070974 TENS2_HUMAN (31-532): 2.18e-36: 150: 11.71		ERBB4_HUMAN (1-1162): 0: 1152: 50.94
+	Hs
		383851 TENS2_HUMAN (31-532): 2.18e-36: 150: 11.71		ERBB2_HUMAN (25-1222): 0: 1067: 39.95
+	Hs
		339206 TACC3_HUMAN (35-803): 1.31e-42: 168: 22.72		EGFR_HUMAN (18-1157): 0: 1041: 42.30
+	Hs
		383754 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		ERBB2_HUMAN (25-1222): 0: 1067: 39.95
+	Hs
		338550 TENS2_HUMAN (31-532): 2.18e-36: 150: 11.71		EGFR_HUMAN (18-1157): 0: 1041: 42.30
+	Hs
		337875 MUC1_HUMAN (9-367): 1e-15: 83.8: 12.22		EGFR_HUMAN (18-1157): 0: 1041: 42.30
+	Hs
		263991 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		RET_HUMAN (518-1072): 1.47e-118: 399: 21.15
+	Hs
		263992 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		IGF1R_HUMAN (577-1061): 4.71e-104: 363: 21.00
+	Hs
		311786 TACC2_HUMAN (7-804): 1.65e-49: 192: 26.54		RET_HUMAN (518-1072): 1.47e-118: 399: 21.15
+	Mm
		222871 MICA3_MOUSE (6-805): 1.45e-40: 163: 11.34		ACK1_MOUSE (677-1328): 5.23e-124: 413: 21.75
+	Mm
		222838 Q3UPB2_MOUSE (48-653): 8.62e-32: 133: 13.24		ACK1_MOUSE (677-1328): 5.23e-124: 413: 21.75
+	Hs
		337335 MUC1_HUMAN (9-367): 1e-15: 83.8: 12.22		ABL1_HUMAN (696-1307): 5.97e-133: 439: 22.51
+	Hs
		665216 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		EPHA2_HUMAN (665-996): 4.18e-104: 356: 29.40
+	Hs
		263990 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		INSR_HUMAN (329-650): 2.27e-22: 106: 16.98
+	Hs
		263999 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		INSRR_HUMAN (329-644): 4.31e-16: 86.4: 14.51
+	Hs
		665392 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		EPHA3_HUMAN (691-978): 1.41e-41: 168: 34.13
+	Rn
		88607 D3ZGN7_RAT (5-805): 2.13e-41: 166: 11.62		INSR_RAT (329-650): 1.42e-20: 101: 16.71
+	Rn
		88517 D3ZAP7_RAT (36-753): 4.08e-38: 156: 10.48		INSR_RAT (329-650): 1.42e-20: 101: 16.71