HitPredict

Interactor 1: LRCH4 (O75427)
Leucine-rich repeat and calponin homology domain-containing protein 4 (Leucine-rich repeat neuronal protein 4) (Leucine-rich neuronal protein)
Gene: LRCH4

Interactor 2: DOCK8 (Q8NF50)
Dedicator of cytokinesis protein 8
Gene: DOCK8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	32203420, 28514442, 33961781, unassigned2213
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 683 Hs			1 2099
+	Hs
		264517 LRCH4_HUMAN (26-683): 1.08e-136: 418: 100.00		DOCK7_HUMAN (7-2092): 0: 2471: 55.37
+	Hs
		1244072 LRCH3_HUMAN (2-141): 9.36e-18: 89.6: 17.14		DOCK8_HUMAN (1-2099): 0: 2775: 100.00
+	Hs
		1244090 LRCH1_HUMAN (1-156): 2.83e-16: 85: 21.02		DOCK8_HUMAN (1-2099): 0: 2775: 100.00
+	Hs
		1138572 LRCH2_HUMAN (367-574): 8.33e-10: 64.2: 6.73		DOCK8_HUMAN (1-2099): 0: 2775: 100.00
+	Hs
		264515 LRCH4_HUMAN (26-683): 1.08e-136: 418: 100.00		DOCK6_HUMAN (4-2092): 0: 2401: 51.16
+	Hs
		1294469 LRCH3_HUMAN (2-141): 9.36e-18: 89.6: 17.14		DOCK7_HUMAN (7-2092): 0: 2471: 55.37
+	Hs
		1298545 LRCH1_HUMAN (1-156): 2.83e-16: 85: 21.02		DOCK7_HUMAN (7-2092): 0: 2471: 55.37
+	Hs
		1138582 LRCH2_HUMAN (367-574): 8.33e-10: 64.2: 6.73		DOCK7_HUMAN (7-2092): 0: 2471: 55.37
+	Hs
		1293663 LRCH3_HUMAN (2-141): 9.36e-18: 89.6: 17.14		DOCK6_HUMAN (4-2092): 0: 2401: 51.16
+	Hs
		1293670 LRCH1_HUMAN (1-156): 2.83e-16: 85: 21.02		DOCK6_HUMAN (4-2092): 0: 2401: 51.16
+	Hs
		1138578 LRCH2_HUMAN (367-574): 8.33e-10: 64.2: 6.73		DOCK6_HUMAN (4-2092): 0: 2401: 51.16
+	Hs
		1138589 LRCH2_HUMAN (367-574): 8.33e-10: 64.2: 6.73		DOCK5_HUMAN (560-867): 2.82e-24: 114: 17.49