HitPredict

Interactor 1: LRCH4 (O75427)
Leucine-rich repeat and calponin homology domain-containing protein 4 (Leucine-rich repeat neuronal protein 4) (Leucine-rich neuronal protein)
Gene: LRCH4

Interactor 2: LRCH3 (Q96II8)
DISP complex protein LRCH3 (Leucine-rich repeat and calponin homology domain-containing protein 3)
Gene: LRCH3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CH~CH, LRR_8~LRR_8
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 683 Hs			1 777
+	Hs
		264523 LRCH4_HUMAN (26-683): 1.08e-136: 418: 100.00		LRCH1_HUMAN (2-226): 1.49e-28: 124: 22.81
+	At
		1114706 PXL1_ARATH (9-581): 2e-78: 272: 13.71		ERECT_ARATH (22-322): 2.59e-57: 213: 24.84
+	Dm
		1181694 SCRIB_DROME (42-566): 6.78e-70: 250: 17.42		SCRIB_DROME (41-512): 1.1e-61: 228: 16.12
+	At
		1325020 PXL1_ARATH (9-581): 2e-78: 272: 13.71		PXL1_ARATH (274-660): 2.2e-49: 189: 9.09
+	At
		1114722 Q9XGZ2_ARATH (34-602): 2.39e-62: 226: 15.27		ERECT_ARATH (22-322): 2.59e-57: 213: 24.84
+	At
		1341098 Q9XGZ2_ARATH (34-602): 2.39e-62: 226: 15.27		BAME2_ARATH (190-674): 4.12e-55: 207: 10.55
+	At
		84507 Q9XGZ2_ARATH (34-602): 2.39e-62: 226: 15.27		GSO1_ARATH (172-635): 1.71e-54: 206: 9.15
+	At
		249727 GSO2_ARATH (1-473): 1.28e-65: 237: 15.35		BAME3_ARATH (13-398): 5.41e-47: 182: 15.54
+	At
		249744 PEPR1_ARATH (1-472): 1.76e-60: 221: 16.36		BAME3_ARATH (13-398): 5.41e-47: 182: 15.54
+	At
		249741 Y1723_ARATH (2-422): 2.79e-55: 206: 16.51		BAME3_ARATH (13-398): 5.41e-47: 182: 15.54
+	At
		83985 Y1723_ARATH (2-422): 2.79e-55: 206: 16.51		Y1743_ARATH (279-674): 6.48e-39: 157: 8.03
+	Hs
		1301465 ERBIN_HUMAN (19-427): 1.91e-56: 210: 16.30		SHOC2_HUMAN (109-289): 1.5e-35: 144: 26.23
+	At
		221539 Q9XGZ2_ARATH (34-602): 2.39e-62: 226: 15.27		Y2317_ARATH (1-267): 4.54e-28: 123: 21.17
+	Hs
		1301436 ERBIN_HUMAN (19-427): 1.91e-56: 210: 16.30		LRRC1_HUMAN (94-325): 2.87e-32: 134: 25.31
+	At
		221776 GSO2_ARATH (1-473): 1.28e-65: 237: 15.35		BAME1_ARATH (1-151): 1.56e-19: 96: 23.53
+	At
		1323635 GSO2_ARATH (1-473): 1.28e-65: 237: 15.35		EMS1_ARATH (427-606): 8.79e-17: 87.1: 11.60
+	At
		221811 Q9XGZ2_ARATH (34-602): 2.39e-62: 226: 15.27		BAME1_ARATH (1-151): 1.56e-19: 96: 23.53
+	At
		221806 PEPR1_ARATH (1-472): 1.76e-60: 221: 16.36		BAME1_ARATH (1-151): 1.56e-19: 96: 23.53
+	Mm
		1193432 ERBIN_MOUSE (19-454): 2.8e-56: 209: 18.32		ERBIN_MOUSE (170-388): 1.08e-15: 83.7: 20.17
+	At
		1352203 Y1723_ARATH (2-422): 2.79e-55: 206: 16.51		BRL2_ARATH (6-151): 4.63e-14: 78.6: 15.65