HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: PAIP1 (Q9H074)
Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1)
Gene: PAIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 479
+	Hs
		1031455 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		PAIP1_HUMAN (1-479): 3.4e-177: 507: 100.00
+	Hs
		516685 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		PAIP1_HUMAN (1-479): 3.4e-177: 507: 100.00
+	Hs
		1119144 PAP1L_HUMAN (6-99): 1.67e-18: 86.3: 21.28		PAIP1_HUMAN (1-479): 3.4e-177: 507: 100.00
+	Mm
		665767 PABP1_MOUSE (2-99): 6.34e-19: 87.9: 17.35		PAIP1_MOUSE (85-479): 6.56e-158: 455: 97.22
+	Hs
		951930 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		IF4G1_HUMAN (51-426): 1.82e-97: 323: 20.66
+	Hs
		979889 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		IF4G1_HUMAN (51-426): 1.82e-97: 323: 20.66
+	Hs
		516476 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		IF4G1_HUMAN (51-426): 1.82e-97: 323: 20.66
+	Hs
		203335 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		IF4G3_HUMAN (28-412): 3.45e-89: 299: 18.20
+	Sc
		376796 PABP_YEAST (2-98): 4.25e-20: 91: 24.74		IF4F1_YEAST (11-426): 1.36e-88: 292: 16.70
+	Dm
		247398 PABP_DROME (2-99): 4.79e-20: 91: 15.31		O61380_DROME (43-441): 1.12e-78: 269: 16.84
+	Sc
		376797 PABP_YEAST (2-98): 4.25e-20: 91: 24.74		IF4F2_YEAST (13-440): 6.93e-80: 268: 14.35
+	Dm
		970869 RBP1_DROME (1-85): 1.86e-20: 86.5: 36.05		Q5KTT4_DROME (55-385): 6.03e-71: 247: 18.31
+	Dm
		597074 PABP_DROME (2-99): 4.79e-20: 91: 15.31		Q9VCH1_DROME (117-377): 5.52e-63: 224: 18.57
+	Pf
		1211776 Q8I5H4_PLAF7 (5-76): 4.34e-17: 82.5: 30.56		Q8IIS9_PLAF7 (132-385): 1.42e-53: 196: 16.91
+	Dm
		970867 RBP1_DROME (1-85): 1.86e-20: 86.5: 36.05		Q0E996_DROME (217-385): 1.54e-40: 157: 21.76