HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: MK67I (Q9BYG3)
MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar phosphoprotein Nopp34) (Nucleolar protein interacting with the FHA domain of pKI-67) (hNIFK)
Gene: NIFK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005694 - chromosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 293
+	Mm
		1265061 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		MK67I_MOUSE (1-293): 5.78e-59: 192: 55.17
+	Mm
		665768 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PABP1_MOUSE (35-225): 2.47e-40: 149: 14.14
+	Mm
		1112470 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PUF60_MOUSE (31-234): 4.52e-30: 120: 17.96
+	Hs
		268323 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96
+	Mm
		936695 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		ELAV1_MOUSE (26-127): 1.55e-25: 105: 20.59
+	Sc
		630883 NLE1_YEAST (4-263): 1.23e-51: 183: 14.05		NOP15_YEAST (14-185): 3.16e-37: 133: 30.64
+	Hs
		1281369 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		MK67I_HUMAN (1-293): 8.07e-53: 176: 100.00
+	Hs
		1288290 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		MK67I_HUMAN (1-293): 8.07e-53: 176: 100.00
+	Hs
		1316912 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		MK67I_HUMAN (1-293): 8.07e-53: 176: 100.00
+	Hs
		1281457 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96
+	Hs
		903196 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		516438 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		1031492 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		516733 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		1327900 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		CSTFT_HUMAN (46-229): 2.35e-38: 144: 19.60
+	Hs
		903585 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96
+	Hs
		642805 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		ELAV4_HUMAN (144-223): 1.03e-10: 63.6: 8.54