Interactor 1: MTHR2 (O74927)
Methylenetetrahydrofolate reductase 2 (EC 1.5.1.53)
Gene: met11
Interactor 2: MTHR1 (Q10258)
Methylenetetrahydrofolate reductase 1 (EC 1.5.1.20)
Gene: met9
Species: Schizosaccharomyces pombe 972h-
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26771498 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | MTHFR~MTHFR, MTHFR~MTHFR_C, MTHFR_C~MTHFR_C |
| Common GO terms | GO:0004489 - methylenetetrahydrofolate reductase [NAD(P)H] activity GO:0009086 - methionine biosynthetic process GO:0035999 - tetrahydrofolate interconversion GO:0071949 - FAD binding GO:0106313 - methylenetetrahydrofolate reductase (NADPH) activity |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
