HitPredict

Interactor 1: EIF3G (O75821)
Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) (eIF-3-delta) (eIF3 p42) (eIF3 p44)
Gene: EIF3G

Interactor 2: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 320 Hs			1 2229
+	Hs
		516546 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		PRC2B_HUMAN (1-2229): 0: 619: 100.00
+	Hs
		275962 EIF3G_HUMAN (1-320): 2.71e-93: 281: 100.00		PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12
+	Hs
		275870 EIF3G_HUMAN (1-320): 2.71e-93: 281: 100.00		EIF3A_HUMAN (962-1409): 3.68e-26: 120: 14.63
+	Hs
		275925 EIF3G_HUMAN (1-320): 2.71e-93: 281: 100.00		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Mm
		612556 EIF3G_MOUSE (1-320): 5.56e-92: 278: 98.44		EIF3A_MOUSE (842-1525): 6.47e-14: 80.2: 11.41
+	Hs
		275819 EIF3G_HUMAN (1-320): 2.71e-93: 281: 100.00		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		965152 PABP3_HUMAN (230-320): 1.07e-21: 97.6: 24.18		ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29
+	Hs
		516749 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		1020354 ELAV2_HUMAN (229-316): 7.55e-22: 96.4: 27.78		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		516766 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12
+	Hs
		1288650 PABP5_HUMAN (243-319): 7.67e-17: 82.1: 23.38		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		1077540 ELAV1_HUMAN (228-303): 5.65e-15: 76.4: 30.26		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		1031405 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		516609 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		516406 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		820908 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24