HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 400
+	Hs
		277114 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		1326760 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		1045510 SPTN1_HUMAN (103-481): 2.5e-55: 202: 14.59		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		1270607 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		125613 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		808589 SPTN1_HUMAN (103-481): 2.5e-55: 202: 14.59		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		125533 TM1L2_HUMAN (1-466): 2.13e-88: 282: 17.19		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		125035 TOM1_HUMAN (1-444): 1.01e-80: 262: 17.68		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		1173029 TM1L2_HUMAN (1-466): 2.13e-88: 282: 17.19		SMUF1_HUMAN (55-362): 3.85e-51: 184: 16.62
+	Hs
		241199 TOM1_HUMAN (1-444): 1.01e-80: 262: 17.68		SMUF1_HUMAN (55-362): 3.85e-51: 184: 16.62
+	Hs
		1294876 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		1078893 ITSN1_HUMAN (188-414): 1.91e-46: 176: 22.50		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		1045530 SPTN1_HUMAN (103-481): 2.5e-55: 202: 14.59		SMUF1_HUMAN (55-362): 3.85e-51: 184: 16.62
+	Hs
		808171 TM1L2_HUMAN (1-466): 2.13e-88: 282: 17.19		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		1045518 SPTN1_HUMAN (103-481): 2.5e-55: 202: 14.59		SAV1_HUMAN (2-252): 3.57e-48: 169: 15.89
+	Hs
		241153 TOM1_HUMAN (1-444): 1.01e-80: 262: 17.68		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Sc
		765278 VPS27_YEAST (1-488): 4.18e-59: 208: 16.02		RSP5_YEAST (60-356): 4.36e-33: 133: 13.24
+	Sc
		753622 HSE1_YEAST (15-449): 6.92e-53: 187: 19.56		RSP5_YEAST (60-356): 4.36e-33: 133: 13.24
+	Hs
		808298 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		125001 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46