Protein: PROP1
Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor)

Gene: PROP1
Organism: Homo sapiens
Interactions: 67
UniProt ID: O75360

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

277084

HXA1
Homeobox protein Hox-A1

2

20

High-throughput

0.783

High

277090

PO6F2
POU domain, class 6, transcription factor 2

2

20

High-throughput

0.783

High

277114

OLIG3
Oligodendrocyte transcription factor 3

2

3

High-throughput

0.783

High

277137

TBX22
T-box transcription factor TBX22

2

16

High-throughput

0.783

High

277093

TLE5
TLE family member 5

3

20

Small-scale

0.658

High

277076

PROP1
Homeobox protein prophet of Pit-1

1

14

High-throughput

0.621

High

63588

PSB11
Proteasome subunit beta type-11

2

1

High-throughput

0.606

High

277081

PSB4
Proteasome subunit beta type-4

2

3

High-throughput

0.606

High

277085

HNRPF
Heterogeneous nuclear ribonucleoprotein F

2

4

High-throughput

0.606

High

277087

SUMO1
Small ubiquitin-related modifier 1

2

4

High-throughput

0.606

High

277089

RNF4
E3 ubiquitin-protein ligase RNF4

2

4

High-throughput

0.606

High

277097

DAZP2
DAZ-associated protein 2

2

2

High-throughput

0.606

High

277127

TEKT4
Tektin-4

2

6

High-throughput

0.606

High

277129

TET5B
Terminal nucleotidyltransferase 5B

2

2

High-throughput

0.606

High

277131

ZN503
Zinc finger protein 503

2

3

High-throughput

0.606

High

277132

TEKT5
Tektin-5

2

6

High-throughput

0.606

High

277133

HDHD3
Haloacid dehalogenase-like hydrolase domain-containing protein 3

2

1

High-throughput

0.606

High

277138

MAGD1
Melanoma-associated antigen D1

2

1

High-throughput

0.606

High

277104

INT11
Integrator complex subunit 11

2

0

High-throughput

0.580

High

277106

CMI2A
Ciliary microtubule inner protein 2A

2

0

High-throughput

0.580

High

277122

BATF2
Basic leucine zipper transcriptional factor ATF-like 2

2

0

High-throughput

0.580

High

277124

SMIP6
Sperm microtubule inner protein 6

2

0

High-throughput

0.580

High

277082

CTNB1
Catenin beta-1

1

3

Small-scale

0.561

High

70053

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.553

High

277077

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

2

4

High-throughput

0.553

High

277100

KR197
Keratin-associated protein 19-7

2

3

High-throughput

0.553

High

277102

SMUG1
Single-strand selective monofunctional uracil DNA glycosylase

2

1

High-throughput

0.553

High

277103

ACTMP
Actin maturation protease

2

1

High-throughput

0.553

High

277108

UFSP1
Ufm1-specific protease 1

2

3

High-throughput

0.553

High

277109

CA094
Uncharacterized protein C1orf94

2

1

High-throughput

0.553

High

277119

KRA81
Keratin-associated protein 8-1

2

2

High-throughput

0.553

High

277120

TRI42
Tripartite motif-containing protein 42

2

10

High-throughput

0.553

High

277123

MET27
Methyltransferase-like protein 27

2

1

High-throughput

0.553

High

277125

ABHDB
sn-1-specific diacylglycerol lipase ABHD11

2

1

High-throughput

0.553

High

277128

F168A
Protein FAM168A

2

2

High-throughput

0.553

High

277130

PKHB2
Pleckstrin homology domain-containing family B member 2

2

1

High-throughput

0.553

High

277134

TINAL
Tubulointerstitial nephritis antigen-like

2

1

High-throughput

0.553

High

277135

CFA68
Cilia- and flagella-associated protein 68

2

1

High-throughput

0.553

High

277092

UBE3A
Ubiquitin-protein ligase E3A

1

3

High-throughput

0.494

High

277088

UBC9
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.481

High

277096

NR1D2
Nuclear receptor subfamily 1 group D member 2

1

20

High-throughput

0.481

High

277115

R144B
E3 ubiquitin-protein ligase RNF144B

1

2

High-throughput

0.481

High

277091

TLE1
Transducin-like enhancer protein 1

1

20

Small-scale

0.479

High

277098

KRA63
Keratin-associated protein 6-3

1

1

High-throughput

0.470

High

277107

Q6NSM0
NR1D2 protein

1

13

High-throughput

0.470

High

277113

Q7KZS0
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.470

High

277079

HSP7C
Heat shock cognate 71 kDa protein

1

4

Small-scale

0.457

High

277086

ATN1
Atrophin-1

1

20

Small-scale

0.457

High

277112

KCTD1
BTB/POZ domain-containing protein KCTD1

1

2

Small-scale

0.457

High

277118

KR131
Keratin-associated protein 13-1

1

3

High-throughput

0.439

High

277083

AMPH
Amphiphysin

1

7

Small-scale

0.417

High

277094

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

3

Small-scale

0.417

High

277095

CNTN1
Contactin-1

1

2

Small-scale

0.417

High

277136

NCDN
Neurochondrin

1

1

Small-scale

0.417

High

66098

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

2

0

High-throughput

0.316

High

277078

CRBA1
Beta-crystallin A3 [Cleaved into: Beta-crystallin A3, isoform A1, Delta4 form; Beta-crystallin A3, isoform A1, Delta7 form; Beta-crystallin A3, isoform A1, Delta8 form]

2

0

High-throughput

0.316

High

277080

ARSA
Arylsulfatase A

2

0

High-throughput

0.316

High

277099

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

277105

TMM42
Transmembrane protein 42

2

0

High-throughput

0.316

High

277110

CF015
Uncharacterized protein C6orf15

2

0

High-throughput

0.316

High

277111

CX6B2
Cytochrome c oxidase subunit 6B2

2

0

High-throughput

0.316

High

277116

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

0

High-throughput

0.316

High

277117

KR191
Keratin-associated protein 19-1

2

0

High-throughput

0.316

High

277126

OXER1
Oxoeicosanoid receptor 1

2

0

High-throughput

0.316

High

277101

KHDC1
KH homology domain-containing protein 1

1

0

High-throughput

0.251

Low

277121

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025