Interactor 1: DHRS3 (O75911)
Short-chain dehydrogenase/reductase 3 (EC 1.1.1.300) (DD83.1) (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) (Retinol dehydrogenase 17) (Short chain dehydrogenase/reductase family 16C member 1)
Gene: DHRS3

Interactor 2: DHRS4 (Q9BTZ2)
Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase) (CR) (NADPH-dependent retinol dehydrogenase/reductase) (NRDR) (humNRDR) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (SCAD-SRL) (Short chain dehydrogenase/reductase family 25C member 2) (Protein SDR25C2) (Short-chain dehydrogenase/reductase family member 4)
Gene: DHRS4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains adh_short~adh_short_C2
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0052650 - all-trans-retinol dehydrogenase (NADP+) activity
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 302
Hs

1 278
+ Hs
+ Ss
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Dm
+ At
+ Ec
+ At
+ Hs
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024