Interactor 1: PIAS1 (O75925)
E3 SUMO-protein ligase PIAS1 (EC 2.3.2.-) (DEAD/H box-binding protein 1) (E3 SUMO-protein transferase PIAS1) (Gu-binding protein) (GBP) (Protein inhibitor of activated STAT protein 1) (RNA helicase II-binding protein)
Gene: PIAS1

Interactor 2: NRIP1 (P48552)
Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140)
Gene: NRIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 35914814
Identification Methods two hybrid, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016607 - nuclear speck
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 651
Hs

1 1158
+ Hs

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Last updated: 15 Jul 2024