HitPredict

Interactor 1: TULP3 (O75386)
Tubby-related protein 3 (Tubby-like protein 3)
Gene: TULP3

Interactor 2: IF122 (Q9HBG6)
Intraflagellar transport protein 122 homolog (WD repeat-containing protein 10) (WD repeat-containing protein 140)
Gene: IFT122

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	28514442, 27173435, 33187986, 33961781, 27932497, unassigned3799
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001843 - neural tube closure GO:0005654 - nucleoplasm GO:0005929 - cilium GO:0036064 - ciliary basal body GO:0045879 - negative regulation of smoothened signaling pathway and 1 others more... GO:0061512 - protein localization to cilium
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 442 Hs			1 1241
+	Hs
		131079 TULP2_HUMAN (111-436): 1.75e-139: 411: 43.58		IF122_HUMAN (1-1241): 0: 1041: 100.00
+	Hs
		279528 TULP3_HUMAN (1-442): 0: 675: 100.00		WDR35_HUMAN (17-1098): 8.37e-163: 518: 15.65
+	Hs
		131082 TULP2_HUMAN (111-436): 1.75e-139: 411: 43.58		WDR35_HUMAN (17-1098): 8.37e-163: 518: 15.65
+	Hs
		279426 TULP3_HUMAN (1-442): 0: 675: 100.00		WDR19_HUMAN (20-1101): 1.01e-37: 156: 10.99
+	Hs
		279485 TULP3_HUMAN (1-442): 0: 675: 100.00		TBL1R_HUMAN (123-362): 1.1e-35: 145: 11.42
+	Hs
		279466 TULP3_HUMAN (1-442): 0: 675: 100.00		IF140_HUMAN (240-642): 2.51e-18: 93.6: 11.49
+	Hs
		131070 TULP2_HUMAN (111-436): 1.75e-139: 411: 43.58		WDR19_HUMAN (20-1101): 1.01e-37: 156: 10.99
+	Hs
		131073 TULP2_HUMAN (111-436): 1.75e-139: 411: 43.58		IF140_HUMAN (240-642): 2.51e-18: 93.6: 11.49