Protein: 3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31)

Gene: 3HIDH, HIBADH
Organism: Homo sapiens
Interactions: 65
UniProt ID: P31937

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006574 - valine catabolic process
GO:0008442 - 3-hydroxyisobutyrate dehydrogenase activity
GO:0050661 - NADP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

644385

PPLA
Cardiac phospholamban

2

0

High-throughput

0.580

High

682457

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

2

0

High-throughput

0.580

High

682416

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

1

5

Small-scale

0.575

High

682447

ZN692
Zinc finger protein 692

2

1

High-throughput

0.574

High

306762

VAMP5
Vesicle-associated membrane protein 5

2

2

High-throughput

0.553

High

364184

TFR1
Transferrin receptor protein 1

2

1

High-throughput

0.553

High

682420

VAMP2
Vesicle-associated membrane protein 2

2

2

High-throughput

0.553

High

682434

CLC2A
C-type lectin domain family 2 member A

2

1

High-throughput

0.553

High

682437

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

1

High-throughput

0.553

High

682441

AQP3
Aquaporin-3

2

3

High-throughput

0.553

High

682445

AMELY
Amelogenin, Y isoform

2

1

High-throughput

0.553

High

682438

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

682446

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.513

High

682417

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.504

High

296272

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

1

High-throughput

0.489

High

444031

A2AP
Alpha-2-antiplasmin

1

1

High-throughput

0.489

High

682428

ECM1
Extracellular matrix protein 1

1

1

High-throughput

0.489

High

682444

CREL1
Protein disulfide isomerase CRELD1

1

1

High-throughput

0.489

High

682458

DAPP1
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

1

2

High-throughput

0.489

High

682422

Q08AM2
ADAM33 protein

1

1

High-throughput

0.470

High

682429

Q59EV6
Carboxypeptidase

1

1

High-throughput

0.470

High

496410

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High

495900

PPGB
Lysosomal protective protein

1

1

High-throughput

0.439

High

682442

TRI63
E3 ubiquitin-protein ligase TRIM63

1

3

Small-scale

0.439

High

682449

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

1

High-throughput

0.439

High

682418

CDK7
Cyclin-dependent kinase 7

1

2

High-throughput

0.437

High

682427

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

682436

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

682448

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

682453

BIRC6
Baculoviral IAP repeat-containing protein 6

1

3

Small-scale

0.437

High

682426

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

0

Small-scale

0.426

High

682421

1433Z
14-3-3 protein zeta/delta

1

2

Small-scale

0.417

High

146952

C2C2L
Phospholipid transfer protein C2CD2L

2

0

High-throughput

0.316

High

151549

GOSR2
Golgi SNAP receptor complex member 2

2

0

High-throughput

0.316

High

242226

PRAF2
PRA1 family protein 2

2

0

High-throughput

0.316

High

263178

SC22B
Vesicle-trafficking protein SEC22b

2

0

High-throughput

0.316

High

305369

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.316

High

316376

SFT2B
Vesicle transport protein SFT2B

2

0

High-throughput

0.316

High

318462

CDS2
Phosphatidate cytidylyltransferase 2

2

0

High-throughput

0.316

High

426769

ASGR1
Asialoglycoprotein receptor 1

2

0

High-throughput

0.316

High

450639

PAEP
Glycodelin

2

0

High-throughput

0.316

High

596871

MAL
Myelin and lymphocyte protein

2

0

High-throughput

0.316

High

602500

COMT
Catechol O-methyltransferase

2

0

High-throughput

0.316

High

682419

EFNA5
Ephrin-A5

2

0

High-throughput

0.316

High

682424

PTC1
Protein patched homolog 1

2

0

High-throughput

0.316

High

682425

SCRB2
Lysosome membrane protein 2

2

0

High-throughput

0.316

High

682430

RTP2
Receptor-transporting protein 2

2

0

High-throughput

0.316

High

682432

CNIH2
Protein cornichon homolog 2

2

0

High-throughput

0.316

High

682433

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.316

High

682435

SNORC
Protein SNORC

2

0

High-throughput

0.316

High

682440

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.316

High

682443

CKLF7
CKLF-like MARVEL transmembrane domain-containing protein 7

2

0

High-throughput

0.316

High

682450

TM6S2
Transmembrane 6 superfamily member 2

2

0

High-throughput

0.316

High

682451

TM222
Transmembrane protein 222

2

0

High-throughput

0.316

High

682452

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

682455

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

682456

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.316

High

682459

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.316

High

135734

EST2
Cocaine esterase

1

0

High-throughput

0.279

Low

246101

RNH1
Ribonuclease H1

1

0

High-throughput

0.279

Low

682431

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

682439

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.279

Low

682454

SNTG1
Gamma-1-syntrophin

1

0

High-throughput

0.279

Low

682423

CUL4A
Cullin-4A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024