HitPredict

Interactor 1: GLRX3 (O76003)
Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2)
Gene: GLRX3

Interactor 2: KRA44 (Q9BYR3)
Keratin-associated protein 4-4 (Keratin-associated protein 4-13) (Keratin-associated protein 4.13) (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.4)
Gene: KRTAP4-4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 335 Hs			1 166
+	Hs
		280464 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KRA47_HUMAN (1-166): 2.55e-31: 112: 54.22
+	Hs
		280454 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KR412_HUMAN (1-166): 1.13e-30: 111: 63.18
+	Hs
		280424 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KRA13_HUMAN (2-165): 1.33e-27: 102: 36.36
+	Hs
		280376 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KR109_HUMAN (3-156): 1.49e-24: 97.9: 33.14
+	Hs
		280463 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KR411_HUMAN (4-131): 1.38e-24: 95.9: 43.14
+	Hs
		280467 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KRA42_HUMAN (29-166): 2.7e-25: 95.9: 68.12
+	Hs
		280373 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KR103_HUMAN (2-141): 2.41e-23: 93.2: 34.42
+	Hs
		280374 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KR105_HUMAN (14-166): 1.68e-22: 92.1: 33.33
+	Hs
		280465 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KRA45_HUMAN (3-166): 4.76e-19: 81.3: 46.95
+	Hs
		280375 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KR108_HUMAN (19-165): 2.65e-18: 80.9: 28.81
+	Hs
		280461 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KRA93_HUMAN (2-151): 2.17e-17: 76.3: 37.42
+	Hs
		280372 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KR101_HUMAN (32-166): 6.51e-15: 72: 30.22
+	Hs
		280377 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KR10B_HUMAN (3-136): 3.54e-14: 70.1: 29.01
+	Hs
		280460 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KRA98_HUMAN (2-126): 1.54e-13: 66.3: 35.20
+	Hs
		280462 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KRA92_HUMAN (3-116): 3.48e-12: 62.8: 43.36
+	Hs
		280371 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		KR123_HUMAN (34-126): 2.53e-09: 53.6: 31.18
+	Hs
		1055295 PDIA5_HUMAN (3-214): 7.7e-37: 140: 17.90		KRA13_HUMAN (2-165): 1.33e-27: 102: 36.36
+	Hs
		888867 PDIA5_HUMAN (3-214): 7.7e-37: 140: 17.90		KR103_HUMAN (2-141): 2.41e-23: 93.2: 34.42
+	Hs
		889244 PDIA5_HUMAN (3-214): 7.7e-37: 140: 17.90		KR107_HUMAN (11-165): 6.43e-20: 86.7: 26.34
+	Hs
		889086 Q86UY0_HUMAN (5-115): 1.21e-28: 115: 19.83		KR105_HUMAN (14-166): 1.68e-22: 92.1: 33.33