HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16055720
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016363 - nuclear matrix GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 707
+	Hs
		280625 PR40A_HUMAN (1-957): 3.8e-106: 353: 100.00		NONO_HUMAN (265-707): 1.86e-71: 241: 56.76
+	Hs
		280750 PR40A_HUMAN (1-957): 3.8e-106: 353: 100.00		PSPC1_HUMAN (230-707): 4.14e-63: 221: 51.77
+	Hs
		132010 WWP2_HUMAN (2-352): 2.92e-41: 165: 16.30		PABP4_HUMAN (291-694): 6.31e-83: 277: 17.75
+	Hs
		1144483 MYO5C_HUMAN (444-946): 4.79e-47: 185: 15.47		NONO_HUMAN (265-707): 1.86e-71: 241: 56.76
+	Hs
		163705 TCRG1_HUMAN (6-820): 3.21e-41: 166: 16.26		SFPQ_HUMAN (1-707): 1.32e-75: 259: 100.00
+	Hs
		131734 WWP2_HUMAN (2-352): 2.92e-41: 165: 16.30		SFPQ_HUMAN (1-707): 1.32e-75: 259: 100.00
+	Hs
		655103 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		SFPQ_HUMAN (1-707): 1.32e-75: 259: 100.00
+	Hs
		163773 TCRG1_HUMAN (6-820): 3.21e-41: 166: 16.26		NONO_HUMAN (265-707): 1.86e-71: 241: 56.76
+	Hs
		132050 WWP2_HUMAN (2-352): 2.92e-41: 165: 16.30		NONO_HUMAN (265-707): 1.86e-71: 241: 56.76
+	Hs
		862453 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		PABP3_HUMAN (287-689): 3.05e-72: 248: 17.53
+	Hs
		131699 WWP2_HUMAN (2-352): 2.92e-41: 165: 16.30		PABP1_HUMAN (287-700): 9.38e-68: 236: 16.25
+	Hs
		862150 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		NONO_HUMAN (265-707): 1.86e-71: 241: 56.76
+	Hs
		550167 YAP1_HUMAN (34-410): 1.72e-40: 158: 10.05		PABP1_HUMAN (287-700): 9.38e-68: 236: 16.25
+	Hs
		163813 TCRG1_HUMAN (6-820): 3.21e-41: 166: 16.26		PSPC1_HUMAN (230-707): 4.14e-63: 221: 51.77
+	Hs
		286429 WBP4_HUMAN (102-385): 5.36e-27: 116: 14.68		SFPQ_HUMAN (1-707): 1.32e-75: 259: 100.00
+	Hs
		286465 WBP4_HUMAN (102-385): 5.36e-27: 116: 14.68		NONO_HUMAN (265-707): 1.86e-71: 241: 56.76
+	Hs
		286425 WBP4_HUMAN (102-385): 5.36e-27: 116: 14.68		PABP1_HUMAN (287-700): 9.38e-68: 236: 16.25
+	Hs
		286488 WBP4_HUMAN (102-385): 5.36e-27: 116: 14.68		PSPC1_HUMAN (230-707): 4.14e-63: 221: 51.77
+	Hs
		550415 ITCH_HUMAN (4-297): 3.79e-18: 92.1: 13.95		PABP1_HUMAN (287-700): 9.38e-68: 236: 16.25
+	Dm
		119660 M9PB30_DROME (3-253): 1.19e-21: 104: 8.66		M9PB30_DROME (104-275): 2.03e-10: 66.8: 18.78