Interactor 1: RNF8 (O76064)
E3 ubiquitin-protein ligase RNF8 (hRNF8) (EC 2.3.2.27) (RING finger protein 8) (RING-type E3 ubiquitin transferase RNF8)
Gene: RNF8
Interactor 2: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.67 | 1.00 | 0.819 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FHA~FHA, FHA~Pkinase |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006302 - double-strand break repair GO:0006974 - DNA damage response GO:0031625 - ubiquitin protein ligase binding and 3 others more... |
| Homologous interactions | 9 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
