Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: CIA2B (Q9Y3D0)
Cytosolic iron-sulfur assembly component 2B (MSS19-interacting protein of 18 kDa) (Mitotic spindle-associated MMXD complex subunit MIP18) (Protein FAM96B)
Gene: CIAO2B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 21516116, 28178521, 31229404, 23891004, 25416956, 22678361, 16189514, 23585563, 32296183, 24981860, 37689310, unassigned1353, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid, tandem affinity purification, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FeS_assembly_P~WD40
Common GO terms GO:0005737 - cytoplasm
GO:0007059 - chromosome segregation
GO:0016226 - iron-sulfur cluster assembly
GO:0071817 - MMXD complex
GO:0097361 - cytosolic [4Fe-4S] assembly targeting complex
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 339
Hs

1 163
+ Hs
+ Sc
+ Hs
+ Ce
+ Dm
+ Hs
+ Dm

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Last updated: 15 Jul 2024