HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: RS10 (P46783)
Small ribosomal subunit protein eS10 (40S ribosomal protein S10)
Gene: RPS10

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 165
+	Mm
		993969 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		RS10_MOUSE (1-165): 3.31e-81: 238: 98.79
+	Hs
		285292 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		PLEC_HUMAN (1-150): 1.68e-52: 181: 45.03
+	Mm
		1362785 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		PLEC_MOUSE (1-136): 1.03e-51: 178: 50.65
+	Hs
		860868 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		RS10_HUMAN (1-165): 5.09e-82: 241: 100.00
+	Sc
		673596 NLE1_YEAST (4-263): 2.52e-49: 177: 14.05		RS10A_YEAST (1-107): 3.46e-51: 160: 53.27
+	Hs
		860681 WDR5_HUMAN (335-440): 3.34e-14: 75.4: 15.09		RS10_HUMAN (1-165): 5.09e-82: 241: 100.00
+	Hs
		861010 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		RS10_HUMAN (1-165): 5.09e-82: 241: 100.00
+	Hs
		1143222 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		PLEC_HUMAN (1-150): 1.68e-52: 181: 45.03
+	Sc
		922131 COPA_YEAST (9-295): 5.36e-29: 122: 11.15		RS10A_YEAST (1-107): 3.46e-51: 160: 53.27
+	Sc
		861041 COPA_YEAST (9-295): 5.36e-29: 122: 11.15		RS10B_YEAST (1-107): 4.62e-50: 157: 52.34
+	Hs
		964961 WDR5_HUMAN (335-440): 3.34e-14: 75.4: 15.09		PLEC_HUMAN (1-150): 1.68e-52: 181: 45.03