HitPredict

Interactor 1: HSP74 (O88600)
Heat shock 70 kDa protein 4 (Ischemia responsive 94 kDa protein)
Gene: Hspa4

Interactor 2: RD23B (Q4KMA2)
UV excision repair protein RAD23 homolog B
Gene: Rad23b

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19182904
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 840 Rn			1 415
+	Hs
		714452 HSP74_HUMAN (1-840): 0: 982: 95.83		UBQL2_HUMAN (1-363): 1.82e-46: 170: 12.22
+	Hs
		714237 HSP74_HUMAN (1-840): 0: 982: 95.83		NEDD8_HUMAN (1-64): 8.1e-15: 71.1: 37.50
+	Hs
		320860 HS74L_HUMAN (1-840): 0: 958: 62.38		NEDD8_HUMAN (1-64): 8.1e-15: 71.1: 37.50
+	Hs
		1079556 HS105_HUMAN (1-840): 0: 929: 61.86		NEDD8_HUMAN (1-64): 8.1e-15: 71.1: 37.50
+	Sc
		694350 HSP7F_YEAST (5-697): 8.36e-138: 426: 37.61		RAD23_YEAST (1-413): 1.14e-72: 234: 26.82
+	Rn
		926179 HSP7C_RAT (564-692): 6.31e-19: 93.5: 17.69		RD23B_RAT (1-415): 3.84e-120: 357: 100.00
+	Hs
		503755 HSP7C_HUMAN (564-692): 2.3e-19: 95.1: 18.46		RD23B_HUMAN (1-415): 1.5e-116: 348: 86.51
+	Hs
		503754 HSP7C_HUMAN (564-692): 2.3e-19: 95.1: 18.46		RD23A_HUMAN (1-415): 2.25e-93: 287: 54.46
+	Mm
		561821 HS71L_MOUSE (564-692): 5.55e-20: 97: 22.31		UBQL2_MOUSE (1-363): 8.06e-54: 190: 14.26
+	Mm
		926170 HSP7C_MOUSE (564-692): 6.31e-19: 93.5: 17.69		UBQL2_MOUSE (1-363): 8.06e-54: 190: 14.26
+	Hs
		504912 HSP7C_HUMAN (564-692): 2.3e-19: 95.1: 18.46		UBQL2_HUMAN (1-363): 1.82e-46: 170: 12.22
+	Hs
		714090 HS71L_HUMAN (564-691): 2.01e-19: 95.1: 24.03		UBQL2_HUMAN (1-363): 1.82e-46: 170: 12.22
+	Hs
		474905 HSP7C_HUMAN (564-692): 2.3e-19: 95.1: 18.46		UBB_HUMAN (1-80): 5.99e-31: 120: 30.00
+	Hs
		504136 HSP7C_HUMAN (564-692): 2.3e-19: 95.1: 18.46		NEDD8_HUMAN (1-64): 8.1e-15: 71.1: 37.50
+	Hs
		713983 HS71L_HUMAN (564-691): 2.01e-19: 95.1: 24.03		NEDD8_HUMAN (1-64): 8.1e-15: 71.1: 37.50
+	Hs
		564084 HSP76_HUMAN (563-690): 1.91e-16: 85.8: 20.16		NEDD8_HUMAN (1-64): 8.1e-15: 71.1: 37.50