Interactor 1: HDAC3 (O88895)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-)
Gene: HDAC3

Interactor 2: MECP2 (Q9Z2D6)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 23770565
Identification Methods anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Hist_deacetyl~MBD
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
and 8 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 428
Mm

1 484
+ Hs
+ Mm
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+ Hs
+ Hs
+ Hs
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+ Mm
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+ Hs
+ Hs
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+ Hs

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Last updated: 15 Jul 2024