Interactor 1: PIAS1 (O88907)
E3 SUMO-protein ligase PIAS1 (EC 2.3.2.27) (DEAD/H box-binding protein 1) (Protein inhibitor of activated STAT protein 1) (RING-type E3 ubiquitin transferase PIAS1)
Gene: PIAS1

Interactor 2: P53 (P02340)
Cellular tumor antigen p53 (Tumor suppressor p53)
Gene: Tp53

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.481

The method score is based on:

Property Details
Experiments 16816390
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
and 6 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 651
Mm

1 390
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024