HitPredict

Interactor 1: CD123 (O75794)
Translation initiation factor eIF2 assembly protein (Cell division cycle protein 123 homolog) (Protein D123) (HT-1080) (PZ32)
Gene: CDC123

Interactor 2: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37314216
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 336 Hs			1 189
+	Hs
		293012 CD123_HUMAN (1-336): 0: 567: 100.00		RASH_HUMAN (1-188): 8.44e-87: 254: 86.77
+	Hs
		293011 CD123_HUMAN (1-336): 0: 567: 100.00		RASN_HUMAN (1-189): 3.16e-85: 251: 85.19
+	Hs
		293719 CD123_HUMAN (1-336): 0: 567: 100.00		RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28
+	Hs
		293514 CD123_HUMAN (1-336): 0: 567: 100.00		RAB1A_HUMAN (4-187): 3.14e-74: 223: 34.36
+	Hs
		293508 CD123_HUMAN (1-336): 0: 567: 100.00		RB11A_HUMAN (4-184): 5.8e-73: 220: 33.88
+	Hs
		293517 CD123_HUMAN (1-336): 0: 567: 100.00		RAP1A_HUMAN (1-165): 7.87e-63: 194: 58.08
+	Hs
		293116 CD123_HUMAN (1-336): 0: 567: 100.00		RALA_HUMAN (4-169): 5.39e-58: 182: 53.29
+	Zm
		77478 C0PDY7_MAIZE (1-153): 1.02e-63: 209: 30.98		B4FB55_MAIZE (4-187): 2.72e-74: 224: 31.16