HitPredict

Interactor 1: IPO13 (O94829)
Importin-13 (Imp13) (Karyopherin-13) (Kap13) (Ran-binding protein 13) (RanBP13)
Gene: IPO13

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.873

Property	Details
Experiments	11447110, 21139563, 23435562
Identification Methods	pull down, x-ray crystallography, thermal shift binding
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	IBN_N~UQ_con, Importin_rep~UQ_con, UQ_con~Xpo1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 158
+	Hs
		162612 XPO1_HUMAN (10-963): 6.36e-159: 497: 15.02		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		930334 TNPO1_HUMAN (34-874): 6.73e-121: 391: 13.23		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Dm
		639409 Q9VRV8_DROME (16-874): 3.57e-117: 381: 11.01		UBCD1_DROME (4-157): 4.5e-74: 220: 35.71
+	Sc
		697593 KA122_YEAST (22-939): 9.81e-127: 412: 14.83		UBC9_YEAST (1-156): 3.53e-61: 187: 56.41