Protein: CCR5
C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195)

Gene: CCR5
Organism: Homo sapiens
Interactions: 38
UniProt ID: P51681

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001618 - virus receptor activity
GO:0002407 - dendritic cell chemotaxis
GO:0003779 - actin binding
GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

562884

CCL5
C-C motif chemokine 5

9

20

Small-scale

0.963

High

518822

CCL3
C-C motif chemokine 3

6

20

Small-scale

0.933

High

561030

CCL4
C-C motif chemokine 4

5

20

Small-scale

0.906

High

906991

CXCR4
C-X-C chemokine receptor type 4

4

17

Small-scale

0.893

High

598257

CL3L1
C-C motif chemokine 3-like 1

2

20

Small-scale

0.778

High

906992

CCL8
C-C motif chemokine 8

2

20

Small-scale

0.776

High

562841

CCL2
C-C motif chemokine 2

1

20

Small-scale

0.665

High

906843

CCL11
Eotaxin

1

20

Small-scale

0.665

High

906993

CCL7
C-C motif chemokine 7

1

20

Small-scale

0.665

High

906999

CCL13
C-C motif chemokine 13

1

20

Small-scale

0.665

High

882414

ARRB1
Beta-arrestin-1

1

12

Small-scale

0.647

High

906987

CCR5
C-C chemokine receptor type 5

1

17

Small-scale

0.647

High

191477

CCL16
C-C motif chemokine 16

1

20

Small-scale

0.618

High

835474

CCR2
C-C chemokine receptor type 2

1

17

Small-scale

0.618

High

906998

CCL17
C-C motif chemokine 17

1

20

High-throughput

0.618

High

906989

EMP1
Epithelial membrane protein 1

2

5

High-throughput

0.606

High

378849

CD4
T-cell surface glycoprotein CD4

2

3

Small-scale

0.588

High

700585

PSA5
Proteasome subunit alpha type-5

1

1

Small-scale

0.552

High

832481

ETV5
ETS translocation variant 5

1

1

High-throughput

0.541

High

906995

S20A2
Sodium-dependent phosphate transporter 2

1

1

High-throughput

0.541

High

906996

IL24
Interleukin-24

1

0

High-throughput

0.518

High

906988

STA5B
Signal transducer and activator of transcription 5B

1

6

Small-scale

0.515

High

907000

CST9L
Cystatin-9-like

1

3

High-throughput

0.494

High

136340

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

14

Small-scale

0.479

High

253327

JAK2
Tyrosine-protein kinase JAK2

1

19

Small-scale

0.479

High

297176

PRAF3
PRA1 family protein 3

1

4

Small-scale

0.479

High

390246

FETA
Alpha-fetoprotein

1

2

Small-scale

0.479

High

606458

CEBPB
CCAAT/enhancer-binding protein beta

1

2

Small-scale

0.479

High

772687

MYH9
Myosin-9

1

1

Small-scale

0.479

High

827709

STAT3
Signal transducer and activator of transcription 3

1

6

Small-scale

0.479

High

906994

FAK1
Focal adhesion kinase 1

1

9

Small-scale

0.479

High

906997

ACKR1
Atypical chemokine receptor 1

1

18

Small-scale

0.479

High

257616

PRAF2
PRA1 family protein 2

1

4

Small-scale

0.470

High

230285

CREB3
Cyclic AMP-responsive element-binding protein 3

1

3

Small-scale

0.457

High

250926

TPST1
Protein-tyrosine sulfotransferase 1

1

1

Small-scale

0.437

High

253824

TPST2
Protein-tyrosine sulfotransferase 2

1

1

Small-scale

0.437

High

906990

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025