HitPredict

Interactor 1: TOX4 (O94842)
TOX high mobility group box family member 4 (Epidermal Langerhans cell protein LCP1)
Gene: TOX4

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30415952
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 454
+	Hs
		347960 HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346626 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		345975 HMGB2_HUMAN (139-314): 2.31e-31: 123: 18.38		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		345751 HMGB1_HUMAN (139-302): 5.39e-28: 113: 20.23		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		379986 HMGX4_HUMAN (55-335): 2.61e-40: 157: 20.41		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		379899 HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		379330 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		379037 HMGB2_HUMAN (139-314): 2.31e-31: 123: 18.38		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		175737 HMGB3_HUMAN (150-309): 1.59e-29: 117: 20.96		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		378934 HMGB1_HUMAN (139-302): 5.39e-28: 113: 20.23		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		252934 LEF1_HUMAN (29-321): 4.96e-40: 152: 11.84		MITF_HUMAN (155-450): 1.47e-29: 123: 14.47
+	Mm
		927934 HMGB1_MOUSE (139-302): 5.39e-28: 113: 20.23		SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61
+	Hs
		252909 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		MITF_HUMAN (155-450): 1.47e-29: 123: 14.47
+	Mm
		818776 SOX2_MOUSE (186-480): 7.81e-30: 121: 13.02		TFEB_MOUSE (167-450): 3.76e-30: 123: 14.92
+	Hs
		898205 HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56		MAX_HUMAN (354-454): 1.39e-24: 101: 32.67