HitPredict

Interactor 1: RHBT1 (O94844)
Rho-related BTB domain-containing protein 1
Gene: RHOBTB1

Interactor 2: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0007015 - actin filament organization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 696 Hs			1 285
+	Hs
		297602 RHBT1_HUMAN (1-696): 0: 541: 100.00		TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96
+	Hs
		419042 RHBT2_HUMAN (1-690): 2.28e-168: 502: 67.94		TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00
+	Hs
		451311 RHBT2_HUMAN (1-690): 2.28e-168: 502: 67.94		TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20
+	Hs
		434429 RHBT2_HUMAN (1-690): 2.28e-168: 502: 67.94		TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27
+	Hs
		932046 RHBT2_HUMAN (1-690): 2.28e-168: 502: 67.94		TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96
+	Hs
		451225 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20
+	Hs
		418937 RHOG_HUMAN (12-210): 1.67e-69: 226: 36.63		TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00
+	Hs
		925177 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96
+	Hs
		894128 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65
+	Hs
		931991 RHOG_HUMAN (12-210): 1.67e-69: 226: 36.63		TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96
+	Hs
		894628 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92
+	Hs
		564571 RHOQ_HUMAN (10-213): 9.06e-84: 264: 37.68		MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65
+	Hs
		564758 RHOQ_HUMAN (10-213): 9.06e-84: 264: 37.68		MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92
+	Hs
		925356 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65
+	Hs
		925766 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92
+	Hs
		545725 RAC2_HUMAN (12-219): 3.63e-71: 231: 36.97		MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92
+	Hs
		892702 RAC3_HUMAN (12-208): 1.21e-70: 230: 39.50		MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92
+	Hs
		951494 RHOG_HUMAN (12-210): 1.67e-69: 226: 36.63		MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92
+	Hs
		901094 RHOA_HUMAN (16-215): 2.02e-68: 224: 36.45		MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92