HitPredict

Interactor 1: MICA2 (O94851)
[F-actin]-monooxygenase MICAL2 (EC 1.14.13.225) (MICAL C-terminal-like protein) (Mical-cL) (Molecule interacting with CasL protein 2) (MICAL-2)
Gene: MICAL2

Interactor 2: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29180619
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1957 Hs			1 190
+	Hs
		940929 PLEC_HUMAN (480-1932): 1.04e-79: 296: 13.32		RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00
+	Hs
		598057 FLNA_HUMAN (480-1721): 2.03e-78: 292: 11.59		RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00
+	Hs
		940896 FLNC_HUMAN (480-1721): 6.56e-74: 277: 10.80		RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00
+	Hs
		940792 SPTB2_HUMAN (480-801): 3.1e-57: 222: 19.58		RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00
+	Hs
		521523 ACTN1_HUMAN (480-757): 2e-57: 218: 23.96		RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00
+	Hs
		211562 ACTN4_HUMAN (480-757): 7.37e-57: 217: 22.57		RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00
+	Hs
		584968 PLEC_HUMAN (480-1932): 1.04e-79: 296: 13.32		RO52_HUMAN (120-187): 1.12e-11: 64.3: 34.78
+	Hs
		598237 FLNA_HUMAN (480-1721): 2.03e-78: 292: 11.59		COP1_HUMAN (125-189): 3.88e-12: 65.8: 32.31
+	Hs
		521464 ACTN1_HUMAN (480-757): 2e-57: 218: 23.96		RO52_HUMAN (120-187): 1.12e-11: 64.3: 34.78
+	Hs
		211495 ACTN4_HUMAN (480-757): 7.37e-57: 217: 22.57		RO52_HUMAN (120-187): 1.12e-11: 64.3: 34.78
+	Hs
		585008 MILK2_HUMAN (1807-1957): 5.27e-18: 92.8: 38.41		RO52_HUMAN (120-187): 1.12e-11: 64.3: 34.78