HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0031410 - cytoplasmic vesicle GO:0070062 - extracellular exosome GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 Hs			1 191
+	Hs
		299140 FLOT1_HUMAN (1-427): 3.28e-145: 421: 100.00		RAC1_HUMAN (1-191): 1e-80: 239: 71.88
+	Hs
		299131 FLOT1_HUMAN (1-427): 3.28e-145: 421: 100.00		CDC42_HUMAN (1-191): 2.01e-77: 231: 60.73
+	Hs
		299135 FLOT1_HUMAN (1-427): 3.28e-145: 421: 100.00		RHOA_HUMAN (5-191): 2.01e-77: 231: 55.62
+	Hs
		299050 FLOT1_HUMAN (1-427): 3.28e-145: 421: 100.00		RAC2_HUMAN (1-191): 3.6e-77: 230: 71.35
+	Hs
		299030 FLOT1_HUMAN (1-427): 3.28e-145: 421: 100.00		RHOC_HUMAN (5-191): 1.31e-75: 226: 56.15
+	Hs
		1015436 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00
+	Hs
		988364 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		RAC1_HUMAN (1-191): 1e-80: 239: 71.88
+	Hs
		299130 FLOT1_HUMAN (1-427): 3.28e-145: 421: 100.00		RAC3_HUMAN (1-177): 2.18e-74: 223: 72.88
+	Hs
		299056 FLOT1_HUMAN (1-427): 3.28e-145: 421: 100.00		RHOQ_HUMAN (4-189): 5.77e-73: 220: 56.84
+	Hs
		955161 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		CDC42_HUMAN (1-191): 2.01e-77: 231: 60.73
+	Hs
		962040 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		RHOA_HUMAN (5-191): 2.01e-77: 231: 55.62
+	Hs
		581044 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		RAC2_HUMAN (1-191): 3.6e-77: 230: 71.35
+	Hs
		466249 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		RHOC_HUMAN (5-191): 1.31e-75: 226: 56.15
+	Hs
		953444 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		RAC3_HUMAN (1-177): 2.18e-74: 223: 72.88
+	Hs
		601288 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		RHOQ_HUMAN (4-189): 5.77e-73: 220: 56.84
+	Hs
		690218 STOM_HUMAN (8-217): 8.07e-21: 93.8: 16.67		CDC42_HUMAN (1-191): 2.01e-77: 231: 60.73
+	Hs
		580879 STOM_HUMAN (8-217): 8.07e-21: 93.8: 16.67		RAC2_HUMAN (1-191): 3.6e-77: 230: 71.35
+	Hs
		466113 STOM_HUMAN (8-217): 8.07e-21: 93.8: 16.67		RHOC_HUMAN (5-191): 1.31e-75: 226: 56.15
+	Hs
		690217 STOM_HUMAN (8-217): 8.07e-21: 93.8: 16.67		RAC3_HUMAN (1-177): 2.18e-74: 223: 72.88
+	Hs
		601177 STOM_HUMAN (8-217): 8.07e-21: 93.8: 16.67		RHOQ_HUMAN (4-189): 5.77e-73: 220: 56.84