HitPredict

Interactor 1: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Interactor 2: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28302793, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0008380 - RNA splicing GO:0016607 - nuclear speck
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 941 Hs			1 530
+	Hs
		300155 PRP6_HUMAN (1-941): 0: 610: 100.00		SF3B4_HUMAN (238-395): 5.66e-23: 103: 22.79
+	Hs
		1054569 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Sc
		376625 PRP6_YEAST (4-924): 7.58e-80: 280: 21.50		PABP_YEAST (40-441): 6.66e-53: 190: 12.17
+	Hs
		1054602 SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		1318160 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41
+	Hs
		174886 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Mm
		665754 CTR9_MOUSE (126-536): 5.01e-16: 85.3: 10.12		PABP1_MOUSE (41-426): 4.67e-61: 214: 19.34
+	Hs
		175287 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41
+	Hs
		174583 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	Hs
		174849 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		PABP4_HUMAN (41-422): 3.94e-60: 211: 17.22
+	Sc
		376611 CYC8_YEAST (641-915): 1.29e-13: 77.2: 17.12		PABP_YEAST (40-441): 6.66e-53: 190: 12.17
+	Sc
		376930 RRP5_YEAST (276-524): 4.45e-12: 72.5: 17.28		PABP_YEAST (40-441): 6.66e-53: 190: 12.17
+	Hs
		1020325 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		ELAV2_HUMAN (434-530): 7.45e-16: 81.1: 10.89
+	Hs
		174911 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		SF3B4_HUMAN (238-395): 5.66e-23: 103: 22.79
+	Hs
		175106 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		DAZP1_HUMAN (243-329): 7.18e-19: 90.6: 29.89
+	Hs
		1020334 SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78		ELAV2_HUMAN (434-530): 7.45e-16: 81.1: 10.89
+	Hs
		161904 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93
+	Hs
		175009 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		RBM23_HUMAN (422-503): 5.12e-10: 63.8: 15.12