HitPredict

Interactor 1: MTCL2 (O94964)
Microtubule cross-linking factor 2 (SOGA family member 1) (Suppressor of glucose by autophagy) (Suppressor of glucose, autophagy-associated protein 1) [Cleaved into: N-terminal form; C-terminal 80 kDa form (80-kDa SOGA fragment)]
Gene: MTCL2

Interactor 2: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007059 - chromosome segregation GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1661 Hs			1 589
+	Hs
		672158 MTCL3_HUMAN (53-747): 2.04e-82: 295: 38.50		2AAA_HUMAN (1-589): 2.84e-166: 487: 100.00
+	Hs
		672367 MTCL1_HUMAN (1-1119): 7.77e-57: 220: 33.25		2AAA_HUMAN (1-589): 2.84e-166: 487: 100.00
+	Hs
		148432 CTRO_HUMAN (184-1015): 5.73e-38: 158: 13.74		2AAA_HUMAN (1-589): 2.84e-166: 487: 100.00
+	Hs
		672191 CNTRL_HUMAN (207-738): 4.26e-12: 73.9: 12.66		2AAA_HUMAN (1-589): 2.84e-166: 487: 100.00
+	Hs
		148220 CTRO_HUMAN (184-1015): 5.73e-38: 158: 13.74		SF3B1_HUMAN (12-589): 2.5e-28: 122: 13.20
+	Hs
		149128 CTRO_HUMAN (184-1015): 5.73e-38: 158: 13.74		GCN1_HUMAN (28-589): 5.37e-25: 112: 16.01