Protein: NIP7
60S ribosome subunit biogenesis protein NIP7 homolog (KD93) (Nucleolar pre-rRNA processing protein NIP7)

Gene: NIP7
Organism: Homo sapiens
Interactions: 166
UniProt ID: Q9Y221

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol
GO:0030687 - preribosome, large subunit precursor

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

855262

NOP2
28S rRNA

3

3

High-throughput

0.867

High

1140054

RRS1
Ribosome biogenesis regulatory protein homolog

4

2

High-throughput

0.686

High

1490438

NIP7
60S ribosome subunit biogenesis protein NIP7 homolog

1

0

High-throughput

0.663

High

1006802

SRPK2
SRSF protein kinase 2

2

2

High-throughput

0.628

High

338216

NSA2
Ribosome biogenesis protein NSA2 homolog

1

1

High-throughput

0.618

High

1356056

NOC3L
Nucleolar complex protein 3 homolog

1

3

High-throughput

0.618

High

447592

NPM
Nucleophosmin

2

1

High-throughput

0.611

High

872901

SOX2
Transcription factor SOX-2

2

1

High-throughput

0.611

High

979353

RS6
Small ribosomal subunit protein eS6

2

1

High-throughput

0.611

High

961894

RL37A
Large ribosomal subunit protein eL43

2

0

High-throughput

0.602

High

977110

CNBP
CCHC-type zinc finger nucleic acid binding protein

2

0

High-throughput

0.602

High

984590

RL30
Large ribosomal subunit protein eL30

2

0

High-throughput

0.602

High

1275759

ZCCHV
Zinc finger CCCH-type antiviral protein 1

2

0

High-throughput

0.602

High

694073

RL10
Large ribosomal subunit protein uL16

2

0

High-throughput

0.585

High

1409878

RBM4B
RNA-binding protein 4B

2

0

High-throughput

0.585

High

1411382

LZTS2
Leucine zipper putative tumor suppressor 2

1

1

High-throughput

0.573

High

397246

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

1428591

DDX24
ATP-dependent RNA helicase DDX24

1

2

Small-scale

0.561

High

1447454

ANLN
Anillin

2

0

High-throughput

0.559

High

182391

WDR46
WD repeat-containing protein 46

1

1

High-throughput

0.536

High

287197

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

4

High-throughput

0.536

High

288821

NPM3
Nucleoplasmin-3

1

1

High-throughput

0.536

High

298465

DNJC8
DnaJ homolog subfamily C member 8

1

1

High-throughput

0.536

High

301265

RL1D1
Ribosomal L1 domain-containing protein 1

1

3

High-throughput

0.536

High

429064

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.536

High

522020

H14
Histone H1.4

1

1

High-throughput

0.536

High

596431

H12
Histone H1.2

1

1

High-throughput

0.536

High

785536

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.536

High

976034

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.536

High

985389

RL10A
Large ribosomal subunit protein uL1

1

3

High-throughput

0.536

High

1008941

RED1
Double-stranded RNA-specific editase 1

1

2

High-throughput

0.536

High

1016673

SRSF3
Serine/arginine-rich splicing factor 3

1

3

High-throughput

0.536

High

1027856

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.536

High

1089931

ILF3
Interleukin enhancer-binding factor 3

1

3

High-throughput

0.536

High

1099310

SRSF5
Serine/arginine-rich splicing factor 5

1

2

High-throughput

0.536

High

1099606

SRSF6
Serine/arginine-rich splicing factor 6

1

4

High-throughput

0.536

High

1418646

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

2

High-throughput

0.536

High

1437412

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.536

High

1446900

TF7L2
Transcription factor 7-like 2

1

1

High-throughput

0.536

High

1451040

RBM28
RNA-binding protein 28

1

1

High-throughput

0.536

High

1453900

H2AW
Core histone macro-H2A.2

1

2

High-throughput

0.536

High

210151

CRX
Cone-rod homeobox protein

1

1

High-throughput

0.523

High

354266

ZBED1
E3 SUMO-protein ligase ZBED1

1

0

High-throughput

0.518

High

1386636

OPTN
Optineurin

1

1

High-throughput

0.515

High

141171

NOP56
Nucleolar protein 56

1

0

High-throughput

0.513

High

344374

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.513

High

423475

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.513

High

634697

LMNB1
Lamin-B1

1

0

High-throughput

0.513

High

686528

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.513

High

788821

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

860061

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

898890

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.513

High

960950

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.513

High

970175

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

985955

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

986282

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

1037696

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.513

High

1112227

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.513

High

1119541

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.513

High

1151237

OASL
2'-5'-oligoadenylate synthase-like protein

1

0

High-throughput

0.513

High

1361801

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

1390659

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

1395849

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.513

High

1410780

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.513

High

1428496

REXO4
RNA exonuclease 4

1

0

High-throughput

0.513

High

1447863

DDX21
Nucleolar RNA helicase 2

1

0

High-throughput

0.513

High

1448908

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.513

High

1451832

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.513

High

1460677

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

1461413

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

1461802

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

1462512

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.513

High

1490439

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

1260554

NOL8
Nucleolar protein 8

1

0

Small-scale

0.504

High

708873

PTN4
Tyrosine-protein phosphatase non-receptor type 4

1

0

High-throughput

0.493

High

502594

H2A1
Histone H2A type 1

1

1

High-throughput

0.489

High

1462451

SRPK3
SRSF protein kinase 3

1

2

High-throughput

0.489

High

331425

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

346517

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

4

High-throughput

0.479

High

786941

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

1

High-throughput

0.479

High

998959

H31
Histone H3.1

1

1

High-throughput

0.479

High

1017311

H33
Histone H3.3

1

1

High-throughput

0.479

High

1036000

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1087619

GRSF1
G-rich sequence factor 1

1

1

High-throughput

0.479

High

1089608

ILF2
Interleukin enhancer-binding factor 2

1

1

High-throughput

0.479

High

1138765

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1207463

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.479

High

1215901

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

1335074

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1361262

DNJC9
DnaJ homolog subfamily C member 9

1

1

High-throughput

0.479

High

1367614

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1368683

KAT6A
Histone acetyltransferase KAT6A

1

1

High-throughput

0.479

High

1385923

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

1433131

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.479

High

1438085

RC3H2
Roquin-2

1

1

High-throughput

0.479

High

298121

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.460

High

889682

CLK2
Dual specificity protein kinase CLK2

1

0

High-throughput

0.460

High

1206578

PRC2B
Protein PRRC2B

1

0

High-throughput

0.460

High

1329142

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

0

High-throughput

0.460

High

1372124

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.460

High

1380259

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.460

High

1400101

QKI
KH domain-containing RNA-binding protein QKI

1

0

High-throughput

0.460

High

129566

MEN1
Menin

1

0

High-throughput

0.458

High

157999

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

194397

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

223430

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

248149

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

274810

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.458

High

373523

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

457778

TBB5
Tubulin beta chain

1

0

High-throughput

0.458

High

473188

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

590055

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

644133

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

696888

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

769537

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

770334

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

800175

COIL
Coilin

1

0

High-throughput

0.458

High

810463

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

879624

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

900232

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.458

High

937975

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

971301

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

976674

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

980557

H4
Histone H4

1

0

High-throughput

0.458

High

1100550

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1141054

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1197755

MIDN
Midnolin

1

0

High-throughput

0.458

High

1235576

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.458

High

1290827

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1329016

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.458

High

1329952

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1346992

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1352842

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1384908

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1385652

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1393833

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1413141

THAP7
THAP domain-containing protein 7

1

0

High-throughput

0.458

High

1436564

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1439115

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

0

High-throughput

0.458

High

1451467

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1454363

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1130531

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

419278

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.437

High

328197

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

0

High-throughput

0.426

High

1032887

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.426

High

1313189

ZC3H3
Zinc finger CCCH domain-containing protein 3

2

0

High-throughput

0.318

High

1279990

NECA2
N-terminal EF-hand calcium-binding protein 2

1

0

High-throughput

0.299

High

191867

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.279

Low

657331

KALM
Anosmin-1

1

0

High-throughput

0.279

Low

1015158

ARF5
ADP-ribosylation factor 5

1

0

High-throughput

0.279

Low

1120515

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.279

Low

1178115

RN151
RING finger protein 151

1

0

High-throughput

0.279

Low

1290060

PNM8A
Paraneoplastic antigen-like protein 8A

1

0

High-throughput

0.279

Low

1395740

ZN668
Zinc finger protein 668

1

0

High-throughput

0.279

Low

1398598

ZNF48
Zinc finger protein 48

1

0

High-throughput

0.279

Low

1447070

HINT3
Adenosine 5'-monophosphoramidase HINT3

1

0

High-throughput

0.279

Low

1454203

NHSL3
NHS-like protein 3

1

0

High-throughput

0.279

Low

1459099

ZBT47
Zinc finger and BTB domain-containing protein 47

1

0

High-throughput

0.279

Low

1397933

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

0

High-throughput

0.251

Low

180109

BET1
BET1 homolog

1

0

High-throughput

0.249

Low

294537

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

774713

BASI
Basigin

1

0

High-throughput

0.249

Low

895821

LHX2
LIM/homeobox protein Lhx2

1

0

High-throughput

0.249

Low

1256137

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1393178

PRR11
Proline-rich protein 11

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025