Interactor 1: ZO3 (O95049)
Tight junction protein ZO-3 (Tight junction protein 3) (Zona occludens protein 3) (Zonula occludens protein 3)
Gene: TJP3
Interactor 2: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10575001 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Guanylate_kin~Guanylate_kin, Guanylate_kin~PDZ, Guanylate_kin~SH3_2, PDZ~PDZ, PDZ~SH3_2, SH3_2~SH3_2 |
| Common GO terms | GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction GO:0030054 - cell junction GO:0035633 - maintenance of blood-brain barrier GO:0045216 - cell-cell junction organization and 5 others more... |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
