HitPredict

Interactor 1: REC8 (O95072)
Meiotic recombination protein REC8 homolog (Cohesin Rec8p)
Gene: REC8

Interactor 2: SMC1A (Q14683)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Gene: SMC1A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 24981860, 33961781
Identification Methods affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Rad21_Rec8~SMC_N, Rad21_Rec8_N~SMC_N
Common GO terms GO:0000776 - kinetochore
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0007062 - sister chromatid cohesion
GO:0008278 - cohesin complex
and 2 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 547
Hs

1 1233
+ Hs
+ Mm
+ Hs
+ Mm

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Last updated: 15 Jul 2024