Protein: RTN1
Reticulon-1 (Neuroendocrine-specific protein)

Gene: RTN1
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q16799

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0007420 - brain development
GO:0014069 - postsynaptic density

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1163617

RTN4
Reticulon-4

4

14

High-throughput

0.699

High

1163615

TMT1A
Thiol S-methyltransferase TMT1A

3

3

High-throughput

0.667

High

275522

RTN2
Reticulon-2

2

15

High-throughput

0.628

High

360000

NB5R3
NADH-cytochrome b5 reductase 3

2

3

High-throughput

0.628

High

529894

TAU
Microtubule-associated protein tau

2

3

High-throughput

0.628

High

1163603

SGMR1
Sigma non-opioid intracellular receptor 1

2

1

High-throughput

0.628

High

1163606

TMM43
Transmembrane protein 43

2

1

High-throughput

0.628

High

1163611

DERL2
Derlin-2

2

7

High-throughput

0.628

High

1162318

CEGT
Ceramide glucosyltransferase

2

1

Small-scale

0.614

High

1163589

F241A
Uncharacterized protein FAM241A

3

3

High-throughput

0.604

High

438081

GLPB
Glycophorin-B

2

1

High-throughput

0.574

High

1163594

CTR3
Cationic amino acid transporter 3

2

5

High-throughput

0.574

High

1163600

F210B
Protein FAM210B, mitochondrial

2

1

High-throughput

0.574

High

1163604

PXL2A
Peroxiredoxin-like 2A

2

3

High-throughput

0.574

High

1163607

TMM70
Transmembrane protein 70, mitochondrial

2

2

High-throughput

0.574

High

140287

SDCB1
Syntenin-1

1

1

High-throughput

0.573

High

936184

MANF
Mesencephalic astrocyte-derived neurotrophic factor

1

0

Small-scale

0.561

High

1031394

IFM3
Interferon-induced transmembrane protein 3

2

5

High-throughput

0.558

High

1060174

B2CL1
Bcl-2-like protein 1

1

3

Small-scale

0.552

High

477168

ACM5
Muscarinic acetylcholine receptor M5

1

5

High-throughput

0.541

High

572443

DRD2
D(2) dopamine receptor

1

6

High-throughput

0.541

High

1163616

PKHF2
Pleckstrin homology domain-containing family F member 2

1

5

High-throughput

0.541

High

297209

PRAF3
PRA1 family protein 3

1

10

High-throughput

0.536

High

328930

RTN3
Reticulon-3

1

17

High-throughput

0.536

High

373955

RASN
GTPase NRas

1

18

High-throughput

0.536

High

1147761

DHC24
Delta(24)-sterol reductase

1

3

High-throughput

0.536

High

1163593

UTP15
U3 small nucleolar RNA-associated protein 15 homolog

1

5

High-throughput

0.536

High

106021

APRIO
Alternative prion protein

2

2

High-throughput

0.533

High

458418

ADRB2
Beta-2 adrenergic receptor

1

2

High-throughput

0.494

High

906972

CCR4
C-C chemokine receptor type 4

1

7

High-throughput

0.494

High

936056

PAR2
Proteinase-activated receptor 2

1

9

High-throughput

0.494

High

1163588

FHI1B
FHF complex subunit HOOK-interacting protein 1B

1

1

High-throughput

0.494

High

843602

HD
Huntingtin

1

0

High-throughput

0.493

High

178945

SCAM2
Secretory carrier-associated membrane protein 2

1

4

High-throughput

0.489

High

277707

H2AY
Core histone macro-H2A.1

1

1

High-throughput

0.489

High

329274

LETM1
Mitochondrial proton/calcium exchanger protein

1

4

High-throughput

0.489

High

354341

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

1

High-throughput

0.489

High

462443

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

4

High-throughput

0.489

High

606121

DESM
Desmin

1

2

High-throughput

0.489

High

902842

BLK
Tyrosine-protein kinase Blk

1

4

High-throughput

0.489

High

959335

RAP1B
Ras-related protein Rap-1b

1

13

High-throughput

0.489

High

1065224

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.489

High

1085664

TBL3
Transducin beta-like protein 3

1

4

High-throughput

0.489

High

1163622

WDR3
WD repeat-containing protein 3

1

2

High-throughput

0.489

High

1163625

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

2

High-throughput

0.489

High

173932

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

5

High-throughput

0.479

High

279174

ULK1
Serine/threonine-protein kinase ULK1

1

1

Small-scale

0.479

High

611148

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

5

High-throughput

0.479

High

631252

RAB5A
Ras-related protein Rab-5A

1

13

High-throughput

0.479

High

847545

SSRA
Translocon-associated protein subunit alpha

1

3

High-throughput

0.479

High

891177

GSK3A
Glycogen synthase kinase-3 alpha

1

4

High-throughput

0.479

High

891591

GSK3B
Glycogen synthase kinase-3 beta

1

4

High-throughput

0.479

High

894778

EMD
Emerin

1

2

High-throughput

0.479

High

901837

RAB9A
Ras-related protein Rab-9A

1

18

High-throughput

0.479

High

903932

BAP31
B-cell receptor-associated protein 31

1

3

High-throughput

0.479

High

951173

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

1027018

REEP5
Receptor expression-enhancing protein 5

1

6

High-throughput

0.479

High

1058437

CKAP4
Cytoskeleton-associated protein 4

1

3

High-throughput

0.479

High

1111551

STIM1
Stromal interaction molecule 1

1

2

High-throughput

0.479

High

1163578

LMBRL
Protein LMBR1L

1

3

High-throughput

0.479

High

1163581

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

6

High-throughput

0.479

High

1163585

RETR3
Reticulophagy regulator 3

1

5

Small-scale

0.479

High

1163587

TEX2
Testis-expressed protein 2

1

2

High-throughput

0.479

High

1163590

DHB11
Estradiol 17-beta-dehydrogenase 11

1

10

High-throughput

0.479

High

1163598

LRC59
Leucine-rich repeat-containing protein 59

1

4

High-throughput

0.479

High

1163602

SEC62
Translocation protein SEC62

1

2

High-throughput

0.479

High

1163605

ESYT1
Extended synaptotagmin-1

1

7

High-throughput

0.479

High

1163608

DERL1
Derlin-1

1

7

High-throughput

0.479

High

1163610

LNP
Endoplasmic reticulum junction formation protein lunapark

1

6

High-throughput

0.479

High

1163612

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

5

High-throughput

0.479

High

1163613

RETR1
Reticulophagy regulator 1

1

5

Small-scale

0.479

High

1163620

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

1163621

AMFR
E3 ubiquitin-protein ligase AMFR

1

7

Small-scale

0.479

High

385793

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

6

High-throughput

0.439

High

541514

FGFR1
Fibroblast growth factor receptor 1

1

4

Small-scale

0.439

High

1163595

NDRG1
Protein NDRG1

1

3

Small-scale

0.439

High

533672

CLUS
Clusterin

1

0

Small-scale

0.438

High

1105615

GOGA4
Golgin subfamily A member 4

1

0

Small-scale

0.438

High

189591

STX7
Syntaxin-7

1

4

High-throughput

0.437

High

291358

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.437

High

474706

VIME
Vimentin

1

2

High-throughput

0.437

High

582821

EZRI
Ezrin

1

3

High-throughput

0.437

High

630530

RAB3B
Ras-related protein Rab-3B

1

15

High-throughput

0.437

High

767445

RADI
Radixin

1

2

High-throughput

0.437

High

837639

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

2

High-throughput

0.437

High

896539

VASP
Vasodilator-stimulated phosphoprotein

1

1

High-throughput

0.437

High

901265

RAB7A
Ras-related protein Rab-7a

1

16

High-throughput

0.437

High

1087127

STX4
Syntaxin-4

1

6

High-throughput

0.437

High

1156100

ZYX
Zyxin

1

1

High-throughput

0.437

High

1163579

SYNE3
Nesprin-3

1

2

High-throughput

0.437

High

1163580

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1163583

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.437

High

1163584

PAQR2
Adiponectin receptor protein 2

1

3

Small-scale

0.437

High

1163618

PXMP2
Peroxisomal membrane protein 2

1

1

High-throughput

0.437

High

404811

PRIO
Major prion protein

1

0

High-throughput

0.426

High

211134

CTR4
Cationic amino acid transporter 4

1

5

High-throughput

0.407

High

722469

CTR1
High affinity cationic amino acid transporter 1

1

5

High-throughput

0.407

High

1163592

S7A14
Solute carrier family 7 member 14

1

5

High-throughput

0.407

High

1163599

TM169
Transmembrane protein 169

1

3

High-throughput

0.407

High

1163601

CEP63
Centrosomal protein of 63 kDa

1

2

High-throughput

0.407

High

49650

T120B
Transmembrane protein 120B

2

0

High-throughput

0.328

High

180528

PLS1
Phospholipid scramblase 1

2

0

High-throughput

0.328

High

450177

GDN
Glia-derived nexin

2

0

High-throughput

0.328

High

1163596

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

2

0

High-throughput

0.328

High

243653

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

0

High-throughput

0.279

Low

416747

TYSY
Thymidylate synthase

1

0

High-throughput

0.279

Low

979744

H4
Histone H4

1

0

High-throughput

0.279

Low

1163576

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

0

High-throughput

0.279

Low

1163586

H2A2B
Histone H2A type 2-B

1

0

High-throughput

0.279

Low

1163597

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.279

Low

1163614

NOL11
Nucleolar protein 11

1

0

High-throughput

0.279

Low

1163623

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.279

Low

1163624

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.279

Low

1163609

HDAC8
Histone deacetylase 8

1

0

Small-scale

0.261

Low

1009608

CCL7
C-C motif chemokine 7

1

0

High-throughput

0.249

Low

1163619

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

954820

PSA6
Proteasome subunit alpha type-6

1

0

Small-scale

0.238

Low

1112517

CUL1
Cullin-1

1

0

Small-scale

0.238

Low

1163591

NEUA
N-acylneuraminate cytidylyltransferase

1

0

Small-scale

0.238

Low

1163577

H37
Histone H3-7

1

0

High-throughput

0.232

Low

1163582

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025