HitPredict

Interactor 1: PP4C (O76932)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (EC 3.1.3.16)
Gene: Pp4-19C

Interactor 2: PP4R3 (Q9VFS5)
Serine/threonine-protein phosphatase 4 regulatory subunit 3 (PP4R3) (Protein falafel)
Gene: flfl

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	25562660, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000775 - chromosome, centromeric region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0030289 - protein phosphatase 4 complex GO:0061060 - negative regulation of peptidoglycan recognition protein signaling pathway
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 307 Dm			1 980
+	Hs
		951987 PP4C_HUMAN (1-307): 0: 541: 91.53		P4R3B_HUMAN (3-754): 0: 998: 53.15
+	Hs
		977514 PP2AB_HUMAN (1-307): 0: 528: 62.58		P4R3B_HUMAN (3-754): 0: 998: 53.15
+	Hs
		951993 PP4C_HUMAN (1-307): 0: 541: 91.53		P4R3A_HUMAN (3-702): 0: 978: 59.89
+	Dd
		1200676 PP4C_DICDI (5-307): 0: 530: 83.17		SMEK_DICDI (6-677): 0: 703: 32.91
+	Sc
		734860 PP4C_YEAST (6-307): 1.21e-146: 416: 61.77		PP4R3_YEAST (7-597): 1.9e-154: 479: 24.71