Protein: PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (EC 3.1.3.16) (Phosphatase PP2A-like catalytic subunit PPH3)

Gene: PP4C, PPH3
Organism: Saccharomyces cerevisiae S288C
Interactions: 62
UniProt ID: P32345

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006470 - protein dephosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

734862

PTPA1
Serine/threonine-protein phosphatase 2A activator 1

3

10

Small-scale

0.818

High

734870

TIP41
Type 2A phosphatase activator TIP41

2

5

Small-scale

0.785

High

734866

TAP42
Type 2A phosphatase-associated protein 42

2

20

Small-scale

0.768

High

734860

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

10

5

Small-scale

0.760

High

734849

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

9

0

Small-scale

0.725

High

694499

SPT5
Transcription elongation factor SPT5

3

4

Small-scale

0.671

High

419383

H2A1
Histone H2A.1

3

6

Small-scale

0.662

High

419648

H2A2
Histone H2A.2

3

6

Small-scale

0.650

High

359172

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

2

2

High-throughput

0.621

High

734846

SPT4
Transcription elongation factor SPT4

2

1

Small-scale

0.611

High

646334

RAD53
Serine/threonine-protein kinase RAD53

2

8

Small-scale

0.602

High

381446

H2B2
Histone H2B.2

2

3

Small-scale

0.601

High

734863

MAF1
Repressor of RNA polymerase III transcription MAF1

2

0

Small-scale

0.598

High

664260

SSD1
Protein SSD1

2

0

Small-scale

0.595

High

394340

EF1A
Elongation factor 1-alpha

2

3

High-throughput

0.584

High

734865

FAR11
Factor arrest protein 11

1

4

Small-scale

0.555

High

734850

YHJ3
Uncharacterized protein YHR033W

1

1

High-throughput

0.536

High

734852

SYSM
Serine--tRNA ligase, mitochondrial

1

2

High-throughput

0.536

High

734853

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.536

High

626643

HSP60
Heat shock protein 60, mitochondrial

2

14

High-throughput

0.533

High

564647

STE12
Protein STE12

1

0

High-throughput

0.513

High

386620

TBB
Tubulin beta chain

1

7

High-throughput

0.500

High

408301

GAL1
Galactokinase

1

1

High-throughput

0.500

High

453476

PYR1
Multifunctional protein URA2

1

6

High-throughput

0.500

High

470485

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

4

High-throughput

0.500

High

486082

TBA1
Tubulin alpha-1 chain

1

9

High-throughput

0.500

High

592085

VATB
V-type proton ATPase subunit B

1

5

High-throughput

0.500

High

594907

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

2

High-throughput

0.500

High

598979

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

4

High-throughput

0.500

High

645325

XRN1
5'-3' exoribonuclease 1

1

2

High-throughput

0.500

High

679473

CDC48
Cell division control protein 48

1

8

High-throughput

0.500

High

734851

KSP1
Serine/threonine-protein kinase KSP1

1

20

High-throughput

0.500

High

734871

RUVB2
RuvB-like protein 2

1

7

High-throughput

0.500

High

553960

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.489

High

734854

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.489

High

381011

H2B1
Histone H2B.1

1

3

Small-scale

0.479

High

706465

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

557678

SRS2
ATP-dependent DNA helicase SRS2

1

0

Small-scale

0.460

High

734864

BUD27
Bud site selection protein 27

1

0

Small-scale

0.458

High

366966

ATPB
ATP synthase subunit beta, mitochondrial

1

5

High-throughput

0.457

High

452854

ATPA
ATP synthase subunit alpha, mitochondrial

1

5

High-throughput

0.457

High

644729

CLH
Clathrin heavy chain

1

3

High-throughput

0.457

High

734855

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.457

High

734867

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

2

High-throughput

0.457

High

734869

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

2

High-throughput

0.457

High

481527

HSP73
Heat shock protein SSA3

1

16

High-throughput

0.445

High

510289

HSP77
Import motor subunit, mitochondrial

1

19

High-throughput

0.445

High

523331

HSP71
Heat shock protein SSA1

1

16

High-throughput

0.445

High

526153

HSP72
Heat shock protein SSA2

1

16

High-throughput

0.445

High

544132

SSB1
Ribosome-associated molecular chaperone SSB1

1

16

High-throughput

0.445

High

597066

BIP
Endoplasmic reticulum chaperone BiP

1

16

High-throughput

0.445

High

675801

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

734844

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

734857

CAJ1
Protein CAJ1

1

3

High-throughput

0.445

High

734858

HSP7E
Heat shock protein SSC3, mitochondrial

1

19

High-throughput

0.445

High

734859

SSB2
Ribosome-associated molecular chaperone SSB2

1

16

High-throughput

0.445

High

734847

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

734856

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.407

High

734861

JEM1
DnaJ-like chaperone JEM1

1

1

High-throughput

0.407

High

734848

MTH1
Protein MTH1

1

0

Small-scale

0.292

High

734845

CDC13
Cell division control protein 13

1

0

Small-scale

0.261

Low

734868

FEX1
Fluoride export protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025