Protein: SPF1
Endoplasmic reticulum transmembrane helix translocase (EC 7.4.2.-) (Complexed with DOR1 protein 1) (Endoplasmic reticulum P5A-ATPase) (Sensitivity to the P.farinosa killer toxin protein 1)

Gene: SPF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 80
UniProt ID: P39986

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005801 - cis-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

543798

HSC82
ATP-dependent molecular chaperone HSC82

2

4

High-throughput

0.584

High

701446

SC61A
Protein transport protein SEC61

2

2

High-throughput

0.584

High

747347

PHO88
SRP-independent targeting protein 3

2

1

High-throughput

0.584

High

491326

HSP71
Heat shock protein SSA1

2

5

Small-scale

0.571

High

340683

PGK
Phosphoglycerate kinase

2

0

High-throughput

0.563

High

342935

ENO2
Enolase 2

2

0

High-throughput

0.563

High

494051

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.552

High

766022

HRD3
ERAD-associated E3 ubiquitin-protein ligase component HRD3

1

0

High-throughput

0.518

High

357287

RMAR
Small ribosomal subunit protein uS3m

1

1

High-throughput

0.479

High

366344

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.479

High

389920

VDAC1
Mitochondrial outer membrane protein porin 1

1

2

Small-scale

0.479

High

419891

SNF1
Carbon catabolite-derepressing protein kinase

1

1

Small-scale

0.479

High

513497

PPB
Repressible alkaline phosphatase

1

1

Small-scale

0.479

High

520263

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

1

High-throughput

0.479

High

520342

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

1

High-throughput

0.479

High

541718

SEC63
Protein translocation protein SEC63

1

3

High-throughput

0.479

High

596979

ACO1
Acyl-CoA desaturase 1

1

1

High-throughput

0.479

High

614966

KC12
Casein kinase I homolog 2

1

2

Small-scale

0.479

High

634315

EMC1
ER membrane protein complex subunit 1

1

2

High-throughput

0.479

High

662313

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

679910

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

2

High-throughput

0.479

High

680734

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

698416

EMP24
Endosomal protein P24B

1

5

High-throughput

0.479

High

707489

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

2

High-throughput

0.479

High

732292

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

1

High-throughput

0.479

High

749032

SSH1
Sec sixty-one protein homolog

1

2

High-throughput

0.479

High

753818

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.479

High

761944

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.479

High

765998

ELO3
Fatty acid elongase 3

1

4

High-throughput

0.479

High

766001

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

3

High-throughput

0.479

High

766002

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

1

High-throughput

0.479

High

766004

PMT4
Dolichyl-phosphate-mannose--protein mannosyltransferase 4

1

2

Small-scale

0.479

High

766006

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

766009

HLJ1
Protein HLJ1

1

1

High-throughput

0.479

High

766018

DHR1
Probable ATP-dependent RNA helicase DHR1

1

2

High-throughput

0.479

High

766024

RTK1
Probable serine/threonine-protein kinase RTK1

1

3

Small-scale

0.479

High

766025

PGA3
Plasma membrane-associated coenzyme Q6 reductase PGA3

1

2

High-throughput

0.479

High

400178

CHO2
Phosphatidylethanolamine N-methyltransferase

1

0

Small-scale

0.458

High

411183

PIS
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.458

High

635199

CWH43
Protein CWH43

1

0

High-throughput

0.458

High

688571

ERG2
C-8 sterol isomerase ERG2

1

0

High-throughput

0.458

High

689093

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

Small-scale

0.458

High

707200

SEC66
Translocation protein SEC66

1

0

High-throughput

0.458

High

733702

GPT2
Glycerol-3-phosphate O-acyltransferase 2

1

0

High-throughput

0.458

High

748489

OM14
Mitochondrial outer membrane protein OM14

1

0

Small-scale

0.458

High

752763

LAG1
Ceramide synthase LAG1

1

0

High-throughput

0.458

High

755043

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.458

High

762224

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

765997

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

0

Small-scale

0.458

High

765999

LCB2
Serine palmitoyltransferase 2

1

0

High-throughput

0.458

High

766000

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

766003

PHO86
Inorganic phosphate transporter PHO86

1

0

High-throughput

0.458

High

766008

STE24
CAAX prenyl protease 1

1

0

High-throughput

0.458

High

766010

ERG25
C-4 methylsterol oxidase ERG25

1

0

High-throughput

0.458

High

766011

YG5L
Uncharacterized protein YGR266W

1

0

Small-scale

0.458

High

766012

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

0

High-throughput

0.458

High

766013

ESP1
Separin

1

0

High-throughput

0.458

High

766017

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.458

High

766020

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.458

High

766021

SPC2
Signal peptidase complex subunit 2

1

0

High-throughput

0.458

High

766026

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.458

High

511428

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

694763

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

765996

HSP7E
Heat shock protein SSC3, mitochondrial

1

5

High-throughput

0.445

High

628093

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

664851

BMH1
Protein BMH1

1

2

High-throughput

0.437

High

711110

YKK0
Probable intramembrane protease YKL100C

1

6

High-throughput

0.437

High

745671

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

756930

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.437

High

766014

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.437

High

766016

SXM1
Importin beta SMX1

1

4

High-throughput

0.437

High

731659

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.426

High

766015

GAS3
Probable 1,3-beta-glucanosyltransferase GAS3

1

0

High-throughput

0.282

High

634147

SRO9
RNA-binding protein SRO9

1

0

Small-scale

0.249

Low

634616

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

747067

IST2
Increased sodium tolerance protein 2

1

0

Small-scale

0.249

Low

766019

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

766023

MCA1
Metacaspase-1

1

0

High-throughput

0.249

Low

766005

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

766007

NOP9
Nucleolar protein 9

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024