HitPredict

Interactor 1: GBRAP (O95166)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46)
Gene: GABARAP

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

Property	Details
Experiments	25215947, 30217973
Identification Methods	affinity chromatography technology, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0005776 - autophagosome GO:0005829 - cytosol GO:0005930 - axoneme GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 1298
+	Hs
		891308 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		1319003 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		1319005 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		1315798 MLP3C_HUMAN (5-116): 1.15e-44: 143: 38.60		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		1319001 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		891030 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39