HitPredict

Interactor 1: IPO7 (O95373)
Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7)
Gene: IPO7

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26618866, 17110338
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1038 Hs			1 1480
+	Hs
		178097 IPO8_HUMAN (1-1032): 0: 822: 64.41		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528833 XPO2_HUMAN (2-921): 1.6e-168: 521: 17.50		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529511 TNPO1_HUMAN (12-892): 7.7e-134: 428: 13.08		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529873 IPO11_HUMAN (1-954): 8.02e-127: 412: 15.94		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		127173 IPO5_HUMAN (4-955): 1.57e-121: 400: 11.44		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529589 IPO9_HUMAN (4-996): 5e-121: 398: 15.05		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529129 IMB1_HUMAN (5-785): 2.49e-114: 375: 12.82		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Dm
		1182055 Q9VSD6_DROME (1-1032): 0: 774: 52.79		Q7KTD0_DROME (788-1466): 6.87e-53: 206: 14.95
+	Dm
		1182040 IPO9_DROME (4-983): 5.63e-116: 383: 14.86		Q7KTD0_DROME (788-1466): 6.87e-53: 206: 14.95
+	Dm
		1182048 Q9VN44_DROME (4-956): 3.2e-115: 383: 13.44		Q7KTD0_DROME (788-1466): 6.87e-53: 206: 14.95