HitPredict

Interactor 1: HCN3 (O88705)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3)
Gene: HCN3

Interactor 2: PEX5R (Q8C437)
PEX5-related protein (PEX2-related protein) (PEX5-like protein) (Peroxin-5-related protein) (Tetratricopeptide repeat-containing Rab8b-interacting protein) (Pex5Rp) (TRIP8b)
Gene: Pex5l

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	23382386, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 779 Mm			1 567
+	Hs
		255117 HCN1_HUMAN (28-779): 0: 591: 58.76		PEX5R_HUMAN (7-567): 7.42e-101: 320: 96.79
+	Mm
		312811 HCN2_MOUSE (2-779): 0: 584: 60.00		PEX5R_MOUSE (1-567): 6.47e-103: 323: 100.00
+	Mm
		312839 HCN1_MOUSE (28-779): 0: 566: 56.06		PEX5R_MOUSE (1-567): 6.47e-103: 323: 100.00
+	Mm
		267183 HCN4_MOUSE (41-695): 0: 559: 71.62		PEX5R_MOUSE (1-567): 6.47e-103: 323: 100.00
+	Hs
		1314743 HCN4_HUMAN (41-770): 0: 561: 65.63		PEX5R_HUMAN (7-567): 7.42e-101: 320: 96.79
+	Hs
		254886 HCN1_HUMAN (28-779): 0: 591: 58.76		PEX5_HUMAN (121-565): 1.71e-48: 180: 47.23