HitPredict

Interactor 1: ZFYV9 (O95405)
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)
Gene: ZFYVE9

Interactor 2: LAMP2 (P13473)
Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b)
Gene: LAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019904 - protein domain specific binding GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1425 Hs			1 410
+	Hs
		313491 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		313578 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		527568 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		507089 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		1189529 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		527737 RUFY1_HUMAN (156-763): 1.92e-101: 342: 14.72		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		527556 FGD5_HUMAN (151-872): 3.46e-92: 330: 14.82		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		527754 FYCO1_HUMAN (112-930): 3.66e-80: 293: 12.19		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		527460 EEA1_HUMAN (2-758): 9.63e-69: 257: 12.42		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		527563 RUFY3_HUMAN (138-584): 6.08e-63: 224: 11.45		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		527896 FYV1_HUMAN (570-895): 6.39e-41: 168: 15.25		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		159863 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		1067488 EEA1_HUMAN (2-758): 9.63e-69: 257: 12.42		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		1183401 RUFY3_HUMAN (138-584): 6.08e-63: 224: 11.45		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		1357932 FYV1_HUMAN (570-895): 6.39e-41: 168: 15.25		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95