Protein: SCC3
Cohesin subunit SCC3 (Irregular cell behavior protein 1)

Gene: SCC3, IRR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 55
UniProt ID: P40541

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

826177

SCC1
Sister chromatid cohesion protein 1

19

13

Small-scale

0.764

High

826162

SMC3
Structural maintenance of chromosomes protein 3

9

20

Small-scale

0.748

High

747731

SMC1
Structural maintenance of chromosomes protein 1

8

20

Small-scale

0.746

High

826170

SCC2
Sister chromatid cohesion protein 2

6

4

Small-scale

0.726

High

826160

SCC3
Cohesin subunit SCC3

1

4

Small-scale

0.724

High

826171

PDS5
Sister chromatid cohesion protein PDS5

3

15

Small-scale

0.640

High

739976

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

2

1

High-throughput

0.628

High

817878

IMB4
Importin subunit beta-4

2

0

High-throughput

0.563

High

826183

RAD61
Protein RAD61

2

0

Small-scale

0.559

High

526897

HSP72
Heat shock protein SSA2

2

4

High-throughput

0.552

High

545170

SSB1
Ribosome-associated molecular chaperone SSB1

2

4

High-throughput

0.552

High

818962

SSB2
Ribosome-associated molecular chaperone SSB2

2

4

High-throughput

0.552

High

677684

MRC1
Mediator of replication checkpoint protein 1

1

0

Small-scale

0.537

High

826161

ECO1
N-acetyltransferase ECO1

1

0

Small-scale

0.537

High

524195

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.536

High

419765

H2A2
Histone H2A.2

1

0

High-throughput

0.493

High

826178

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.493

High

806013

LIN1
Protein LIN1

1

0

Small-scale

0.486

High

826164

TOF1
Topoisomerase 1-associated factor 1

1

0

Small-scale

0.480

High

826172

CSM3
Chromosome segregation in meiosis protein 3

1

0

Small-scale

0.480

High

743099

STH1
Nuclear protein STH1/NPS1

1

1

Small-scale

0.479

High

826165

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

826182

SMC6
Structural maintenance of chromosomes protein 6

1

16

High-throughput

0.479

High

826180

HOS1
Histone deacetylase HOS1

1

1

High-throughput

0.464

High

579542

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

594411

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

707323

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

712760

PTP2
Tyrosine-protein phosphatase 2

1

0

High-throughput

0.458

High

747899

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

800656

KPR2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.458

High

826174

SGO1
Shugoshin

1

0

High-throughput

0.458

High

826176

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

826179

REC8
Meiotic recombination protein REC8

1

0

Small-scale

0.458

High

381134

H2B1
Histone H2B.1

1

4

High-throughput

0.445

High

394637

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

450600

FAS1
Fatty acid synthase subunit beta

1

1

High-throughput

0.445

High

481647

HSP73
Heat shock protein SSA3

1

4

High-throughput

0.445

High

676070

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

741741

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

811325

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

826166

H3
Histone H3

1

5

High-throughput

0.445

High

826167

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

1

High-throughput

0.445

High

826168

HOS3
Histone deacetylase HOS3

1

1

High-throughput

0.445

High

826169

ESC1
Silent chromatin protein ESC1

1

4

High-throughput

0.437

High

453638

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

592303

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

747412

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.426

High

752355

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

826181

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

754480

RT05
Small ribosomal subunit protein uS5m

1

0

Small-scale

0.251

Low

677437

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

826175

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

826173

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.238

Low

826163

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025