HitPredict

Interactor 1: BAG4 (O95429)
BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)
Gene: BAG4

Interactor 2: HSF2 (Q03933)
Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2)
Gene: HSF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 457 Hs			1 536
+	Hs
		314028 BAG4_HUMAN (1-457): 0: 698: 100.00		HSF1_HUMAN (3-466): 1.55e-140: 418: 36.76
+	Hs
		324353 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		HSF2_HUMAN (1-536): 0: 622: 100.00
+	Hs
		977935 BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38		HSF2_HUMAN (1-536): 0: 622: 100.00
+	Hs
		324346 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		HSF1_HUMAN (3-466): 1.55e-140: 418: 36.76
+	Hs
		961317 BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38		HSF1_HUMAN (3-466): 1.55e-140: 418: 36.76
+	Hs
		324627 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		Q9HAV2_HUMAN (351-466): 1.56e-31: 121: 32.76